Abstract
Primary central nervous system lymphoma (PCNSL) is generally characterized by a poor prognosis and frequent relapsing disease. Consolidation therapy in the upfront setting usually consists of an autologous stem cell transplantation. We report the case of a 19-year-old Caucasian male who had previously undergone an allogeneic stem cell transplantation with complete engraftment for the treatment of juvenile myelomonocytic leukemia when he was 1 year old. He presented with two episodes of (donor-derived) PCNSL from allogeneic stem cells; however, after induction chemotherapy, he failed to harvest stem cells for the consolidation with autologous stem cell transplantation. He was consolidated successfully with a second allogeneic stem cell transplantation with another donor after conditioning with thiotepa, busulfan, and fludarabine.
Original language | English |
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Pages (from-to) | 366-370 |
Number of pages | 5 |
Journal | Acta Haematologica |
Volume | 147 |
Issue number | 3 |
Early online date | 3 Oct 2023 |
DOIs | |
Publication status | Published - 3 Oct 2023 |
Bibliographical note
Publisher Copyright:© 2023 The Author(s). Published by S. Karger AG, Basel.