Relative undernourishment and food insecurity associations with Plasmodium falciparum among Batwa pygmies in Uganda: Evidence from a cross-sectional survey

Joseph A. Lewnard*, Lea Berrang-Ford, Shuaib Lwasa, Didacus Bambaiha Namanya, Kaitlin A. Patterson, Blánaid Donnelly, Manisha A. Kulkarni, Sherilee L. Harper, Nicholas H. Ogden, Cesar P. Carcamo, James D. Ford, Victoria L. Edge, Alejandro Llanos

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
9 Downloads (Pure)

Abstract

Although malnutrition and malaria co-occur among individuals and populations globally, effects of nutritional status on risk for parasitemia and clinical illness remain poorly understood. We investigated associations between Plasmodium falciparum infection, nutrition, and food security in a cross-sectional survey of 365 Batwa pygmies in Kanungu District, Uganda in January of 2013. We identified 4.1% parasite prevalence among individuals over 5 years old. Severe food insecurity was associated with increased risk for positive rapid immunochromatographic test outcome (adjusted relative risk [ARR] = 13.09; 95% confidence interval [95% CI] = 2.23-76.79). High age/sex-adjusted mid-upper arm circumference was associated with decreased risk for positive test among individuals who were not severely foodinsecure (ARR = 0.37; 95% CI = 0.19-0.69). Within Batwa pygmy communities, where malnutrition and food insecurity are common, individuals who are particularly undernourished or severely food-insecure may have elevated risk for P. falciparum parasitemia. This finding may motivate integrated control of malaria and malnutrition in low-transmission settings.

Original languageEnglish
Pages (from-to)39-49
Number of pages11
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume91
Issue number1
DOIs
Publication statusPublished - Jul 2014
Externally publishedYes

Fingerprint

Dive into the research topics of 'Relative undernourishment and food insecurity associations with Plasmodium falciparum among Batwa pygmies in Uganda: Evidence from a cross-sectional survey'. Together they form a unique fingerprint.

Cite this