Remote hemodynamic guidance before and after left ventricular assist device implantation: Short-Term results from the HEMO-VAD pilot study

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Abstract

Aim: We aimed to assess the safety and feasibility of using CardioMEMS monitoring in patients before and after left ventricular assist device (LVAD) surgery. Patients and methods: Ten patients accepted for elective LVAD surgery were included, received a CardioMEMS at baseline and were categorized based on mean pulmonary artery pressure (mPAP) ?25 mmHg (n = 4) or mPAP >25 mmHg [n = 6]) before LVAD surgery. Results: The combined end point of all-cause mortality, acute kidney injury and/or renal replacement therapy, and right ventricular failure occurred more often in patients with an mPAP >25 mmHg (83 vs 0%, p = 0.017). Conclusion: This pilot study demonstrates that combining CardioMEMS monitoring with LVAD therapy is safe and generates the hypothesis that patients with an mPAP >25 mmHg before LVAD surgery identify a very high-risk group for adverse clinical outcomes.

Original languageEnglish
Pages (from-to)885-898
Number of pages14
JournalFuture Cardiology
Volume17
Issue number5
Early online date7 Jan 2021
DOIs
Publication statusPublished - Aug 2021

Bibliographical note

Funding Information:
This work was supported by Abbott with an independent research grant, partially covering personnel costs. This study was investigator-initiated and was designed, conducted, interpreted and reported independently of the funder by the CRO/sponsor Erasmus University Medical Center. JJ Brugts has received speaker fees from Abbott. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.

Publisher Copyright:
© 2021

Fingerprint

Dive into the research topics of 'Remote hemodynamic guidance before and after left ventricular assist device implantation: Short-Term results from the HEMO-VAD pilot study'. Together they form a unique fingerprint.

Cite this