Reply [to: Hong-Xia et al.]

Laurens A. van Kleef*, Robert J. de Knegt, Willem Pieter Brouwer

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademic


We thank Hong-Xia et al. for their interest in our study showing that metabolic dysfunction-associated fatty liver disease (MAFLD) and excessive alcohol consumption are simultaneously associated with increased risk of all-cause mortality. In their letter, they raised several concerns, which we would like to address. [...]
In conclusion, our study proved the concept of MAFLD being a risk factor independent of alcohol consumption and vice versa. Both MAFLD and excessive alcohol consumption should therefore be addressed in MAFLD disease management.
Original languageEnglish
Pages (from-to)E69-E70
Number of pages2
Issue number4
Early online date25 Aug 2022
Publication statusPublished - Apr 2023

Bibliographical note

Funding Information:
Financial support was provided by the Foundation for Liver and Gastrointestinal Research, Rotterdam, The Netherlands.


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