Reversible severe hepatitis in anorexia nervosa: a case report and overview

Dewkoemar Ramsoekh, Pavel Taimr, Thomas Vanwolleghem

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Mildly elevated transaminases are often observed in anorexia nervosa patients, but severe hepatitis is less common. We suggest that hypoperfusion is the pathogenetic factor that causes severe hepatitis in a patient with a very poor nutritional status and present an overview of previous case reports. In our patient, early initiation of intravenous fluids resulted in rapid recovery of the liver test abnormalities, despite minimal oral caloric intake, the refusal of enteral feeding and the development of a hypoglycemic coma. Two months after admission, transaminases had normalized. Reversible severe hepatitis has been described in most of the cases, with only one anorexia nervosa-related fatal hepatitis. In general, both adequate hydration and gradual enteral feeding with monitoring of electrolytes are essential in the management of anorexia patients with severe hepatitis.
Original languageUndefined/Unknown
Pages (from-to)473-477
Number of pages5
JournalEuropean Journal of Gastroenterology & Hepatology
Issue number4
Publication statusPublished - 2014

Research programs

  • EMC MM-04-20-01
  • EMC MM-04-20-02-A

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