Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy

R C Minnee; W A Bemelman; K A M I Donselaar-van der Pant; J Booij; S ter Meulen; I J M ten Berge; D A Legemate; F J Bemelman; M M Idu

doi:10.1016/j.transproceed.2010.05.163

Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy

R C Minnee, W A Bemelman, K A M I Donselaar-van der Pant, J Booij, S ter Meulen, I J M ten Berge, D A Legemate, F J Bemelman, M M Idu

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Scopus)

Abstract

BACKGROUND: Delayed graft function (DGF) has a negative effect on the results of living-donor kidney transplantation.

OBJECTIVE: To investigate potential risk factors for DGF.

METHODS: This prospective study included 200 consecutive living donors and their recipients between January 2002 and July 2007. Delayed graft function was defined as need for dialysis within the first postoperative week.

RESULTS: Delayed graft function was diagnosed in 12 patients (6%). Intraoperative complications occurred in 10 donors (5%), and postoperative complications in 24 donors (13.5%). One-year kidney graft survival with vs without DGF was 52% and 98%, respectively (P < .002). In donors, 2 univariate risk factors for DGF identified were lower counts per second at peak activity during scintigraphy, and multiple renal veins. In recipients, only 2 or more kidney transplantations and occurrence of an acute rejection episode were important factors. At multivariate analysis, increased risk of DGF was associated with the presence of multiple renal veins (odds ratio, 151.57; 95% confidence interval, 2.53-9093.86) and an acute rejection episode (odds ratio, 78.87; 95% confidence interval, 3.17-1959.62).

CONCLUSION: Hand-assisted laparoscopic donor nephrectomy is a safe procedure. The presence of multiple renal veins and occurrence of an acute rejection episode are independent risk factors for DGF.

Original language	English
Pages (from-to)	2422-6
Number of pages	5
Journal	Transplantation Proceedings
Volume	42
Issue number	7
DOIs	https://doi.org/10.1016/j.transproceed.2010.05.163
Publication status	Published - Sept 2010
Externally published	Yes

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@article{22cf3f60854444bf80cfba420813f46c,

title = "Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy",

abstract = "BACKGROUND: Delayed graft function (DGF) has a negative effect on the results of living-donor kidney transplantation.OBJECTIVE: To investigate potential risk factors for DGF.METHODS: This prospective study included 200 consecutive living donors and their recipients between January 2002 and July 2007. Delayed graft function was defined as need for dialysis within the first postoperative week.RESULTS: Delayed graft function was diagnosed in 12 patients (6%). Intraoperative complications occurred in 10 donors (5%), and postoperative complications in 24 donors (13.5%). One-year kidney graft survival with vs without DGF was 52% and 98%, respectively (P < .002). In donors, 2 univariate risk factors for DGF identified were lower counts per second at peak activity during scintigraphy, and multiple renal veins. In recipients, only 2 or more kidney transplantations and occurrence of an acute rejection episode were important factors. At multivariate analysis, increased risk of DGF was associated with the presence of multiple renal veins (odds ratio, 151.57; 95% confidence interval, 2.53-9093.86) and an acute rejection episode (odds ratio, 78.87; 95% confidence interval, 3.17-1959.62).CONCLUSION: Hand-assisted laparoscopic donor nephrectomy is a safe procedure. The presence of multiple renal veins and occurrence of an acute rejection episode are independent risk factors for DGF.",

author = "Minnee, {R C} and Bemelman, {W A} and {Donselaar-van der Pant}, {K A M I} and J Booij and {ter Meulen}, S and {ten Berge}, {I J M} and Legemate, {D A} and Bemelman, {F J} and Idu, {M M}",

year = "2010",

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doi = "10.1016/j.transproceed.2010.05.163",

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T1 - Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy

AU - Minnee, R C

AU - Bemelman, W A

AU - Donselaar-van der Pant, K A M I

AU - Booij, J

AU - ter Meulen, S

AU - ten Berge, I J M

AU - Legemate, D A

AU - Bemelman, F J

AU - Idu, M M

PY - 2010/9

Y1 - 2010/9

N2 - BACKGROUND: Delayed graft function (DGF) has a negative effect on the results of living-donor kidney transplantation.OBJECTIVE: To investigate potential risk factors for DGF.METHODS: This prospective study included 200 consecutive living donors and their recipients between January 2002 and July 2007. Delayed graft function was defined as need for dialysis within the first postoperative week.RESULTS: Delayed graft function was diagnosed in 12 patients (6%). Intraoperative complications occurred in 10 donors (5%), and postoperative complications in 24 donors (13.5%). One-year kidney graft survival with vs without DGF was 52% and 98%, respectively (P < .002). In donors, 2 univariate risk factors for DGF identified were lower counts per second at peak activity during scintigraphy, and multiple renal veins. In recipients, only 2 or more kidney transplantations and occurrence of an acute rejection episode were important factors. At multivariate analysis, increased risk of DGF was associated with the presence of multiple renal veins (odds ratio, 151.57; 95% confidence interval, 2.53-9093.86) and an acute rejection episode (odds ratio, 78.87; 95% confidence interval, 3.17-1959.62).CONCLUSION: Hand-assisted laparoscopic donor nephrectomy is a safe procedure. The presence of multiple renal veins and occurrence of an acute rejection episode are independent risk factors for DGF.

AB - BACKGROUND: Delayed graft function (DGF) has a negative effect on the results of living-donor kidney transplantation.OBJECTIVE: To investigate potential risk factors for DGF.METHODS: This prospective study included 200 consecutive living donors and their recipients between January 2002 and July 2007. Delayed graft function was defined as need for dialysis within the first postoperative week.RESULTS: Delayed graft function was diagnosed in 12 patients (6%). Intraoperative complications occurred in 10 donors (5%), and postoperative complications in 24 donors (13.5%). One-year kidney graft survival with vs without DGF was 52% and 98%, respectively (P < .002). In donors, 2 univariate risk factors for DGF identified were lower counts per second at peak activity during scintigraphy, and multiple renal veins. In recipients, only 2 or more kidney transplantations and occurrence of an acute rejection episode were important factors. At multivariate analysis, increased risk of DGF was associated with the presence of multiple renal veins (odds ratio, 151.57; 95% confidence interval, 2.53-9093.86) and an acute rejection episode (odds ratio, 78.87; 95% confidence interval, 3.17-1959.62).CONCLUSION: Hand-assisted laparoscopic donor nephrectomy is a safe procedure. The presence of multiple renal veins and occurrence of an acute rejection episode are independent risk factors for DGF.

U2 - 10.1016/j.transproceed.2010.05.163

DO - 10.1016/j.transproceed.2010.05.163

M3 - Article

C2 - 20832519

SN - 0041-1345

VL - 42

SP - 2422

EP - 2426

JO - Transplantation Proceedings

JF - Transplantation Proceedings

IS - 7

ER -

Risk factors for delayed graft function after hand-assisted laparoscopic donor nephrectomy

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