Rituximab for the treatment of glomerulonephritis in hepatitis C associated cryoglobulinaemia

MR Korte; MJ Heerde; Rob de Man; M.G.H. Betjes

Rituximab for the treatment of glomerulonephritis in hepatitis C associated cryoglobulinaemia

MR Korte, MJ Heerde, Rob de Man, M.G.H. Betjes

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

Mixed-type cryoglobulins are strongly associated with hepatitis C virus (HCV) infection and may lead to vasculitis with renal involvement. The treatment of this condition is antiviral therapy for HCV, but this may be ineffective or not tolerated because of side effects. Alternative strategies such as immunosuppressive drugs and plasmapheresis are of limited use, especially in patients after liver transplantation (LTx). We describe an LTx patient with cryoglobulinaemia-associated glomerulonephritis, who was treated successfully with the B cell depleting monoclonal antibody rituximab.

Original language	Undefined/Unknown
Pages (from-to)	27-30
Number of pages	4
Journal	Netherlands Journal of Medicine
Volume	66
Issue number	1
Publication status	Published - 2008

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Cite this

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title = "Rituximab for the treatment of glomerulonephritis in hepatitis C associated cryoglobulinaemia",

abstract = "Mixed-type cryoglobulins are strongly associated with hepatitis C virus (HCV) infection and may lead to vasculitis with renal involvement. The treatment of this condition is antiviral therapy for HCV, but this may be ineffective or not tolerated because of side effects. Alternative strategies such as immunosuppressive drugs and plasmapheresis are of limited use, especially in patients after liver transplantation (LTx). We describe an LTx patient with cryoglobulinaemia-associated glomerulonephritis, who was treated successfully with the B cell depleting monoclonal antibody rituximab.",

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T1 - Rituximab for the treatment of glomerulonephritis in hepatitis C associated cryoglobulinaemia

AU - Korte, MR

AU - Heerde, MJ

AU - de Man, Rob

AU - Betjes, M.G.H.

PY - 2008

Y1 - 2008

N2 - Mixed-type cryoglobulins are strongly associated with hepatitis C virus (HCV) infection and may lead to vasculitis with renal involvement. The treatment of this condition is antiviral therapy for HCV, but this may be ineffective or not tolerated because of side effects. Alternative strategies such as immunosuppressive drugs and plasmapheresis are of limited use, especially in patients after liver transplantation (LTx). We describe an LTx patient with cryoglobulinaemia-associated glomerulonephritis, who was treated successfully with the B cell depleting monoclonal antibody rituximab.

AB - Mixed-type cryoglobulins are strongly associated with hepatitis C virus (HCV) infection and may lead to vasculitis with renal involvement. The treatment of this condition is antiviral therapy for HCV, but this may be ineffective or not tolerated because of side effects. Alternative strategies such as immunosuppressive drugs and plasmapheresis are of limited use, especially in patients after liver transplantation (LTx). We describe an LTx patient with cryoglobulinaemia-associated glomerulonephritis, who was treated successfully with the B cell depleting monoclonal antibody rituximab.

M3 - Article

VL - 66

SP - 27

EP - 30

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

SN - 0300-2977

IS - 1

ER -