Role of anti-Mullerian hormone and bone morphogenetic proteins in the regulation of FSH sensitivity

Jenny Visser; Axel Themmen

doi:10.1016/j.mce.2013.08.012

Role of anti-Mullerian hormone and bone morphogenetic proteins in the regulation of FSH sensitivity

Jenny Visser, Axel Themmen

Internal Medicine

Research output: Contribution to journal › Article › Academic › peer-review

58 Citations (Scopus)

Abstract

The ovary is under control of the hypothalamus and pituitary through the glycoprotein hormones LH and FSH. These hormones undergo a cyclic variation which results in the selection of the species-specific number of follicles that will ovulate during the cycle. Where LH is the main ovulatory hormone and regulator of corpus luteum function, FSH plays an essential role in the cyclic recruitment of the follicles. Within the microenvironment of the ovary, growth factors affect this dominant control of FSH by regulating the FSH sensitivity of individual follicles. In this review we discuss the role of anti-Mullerian hormone (AMH) and bone morphogenetic proteins (BMPs) in this process. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	460-465
Number of pages	6
Journal	Molecular and Cellular Endocrinology
Volume	382
Issue number	1
DOIs	https://doi.org/10.1016/j.mce.2013.08.012
Publication status	Published - 2014

Research programs

EMC MM-01-39-04

Access to Document

10.1016/j.mce.2013.08.012

http://hdl.handle.net/1765/72144

Cite this

@article{37eb5e242eb940e28aa18eb902f4246c,

title = "Role of anti-Mullerian hormone and bone morphogenetic proteins in the regulation of FSH sensitivity",

abstract = "The ovary is under control of the hypothalamus and pituitary through the glycoprotein hormones LH and FSH. These hormones undergo a cyclic variation which results in the selection of the species-specific number of follicles that will ovulate during the cycle. Where LH is the main ovulatory hormone and regulator of corpus luteum function, FSH plays an essential role in the cyclic recruitment of the follicles. Within the microenvironment of the ovary, growth factors affect this dominant control of FSH by regulating the FSH sensitivity of individual follicles. In this review we discuss the role of anti-Mullerian hormone (AMH) and bone morphogenetic proteins (BMPs) in this process. (C) 2013 Elsevier Ireland Ltd. All rights reserved.",

author = "Jenny Visser and Axel Themmen",

year = "2014",

doi = "10.1016/j.mce.2013.08.012",

language = "Undefined/Unknown",

volume = "382",

pages = "460--465",

journal = "Molecular and Cellular Endocrinology",

issn = "0303-7207",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

TY - JOUR

T1 - Role of anti-Mullerian hormone and bone morphogenetic proteins in the regulation of FSH sensitivity

AU - Visser, Jenny

AU - Themmen, Axel

PY - 2014

Y1 - 2014

N2 - The ovary is under control of the hypothalamus and pituitary through the glycoprotein hormones LH and FSH. These hormones undergo a cyclic variation which results in the selection of the species-specific number of follicles that will ovulate during the cycle. Where LH is the main ovulatory hormone and regulator of corpus luteum function, FSH plays an essential role in the cyclic recruitment of the follicles. Within the microenvironment of the ovary, growth factors affect this dominant control of FSH by regulating the FSH sensitivity of individual follicles. In this review we discuss the role of anti-Mullerian hormone (AMH) and bone morphogenetic proteins (BMPs) in this process. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

AB - The ovary is under control of the hypothalamus and pituitary through the glycoprotein hormones LH and FSH. These hormones undergo a cyclic variation which results in the selection of the species-specific number of follicles that will ovulate during the cycle. Where LH is the main ovulatory hormone and regulator of corpus luteum function, FSH plays an essential role in the cyclic recruitment of the follicles. Within the microenvironment of the ovary, growth factors affect this dominant control of FSH by regulating the FSH sensitivity of individual follicles. In this review we discuss the role of anti-Mullerian hormone (AMH) and bone morphogenetic proteins (BMPs) in this process. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

U2 - 10.1016/j.mce.2013.08.012

DO - 10.1016/j.mce.2013.08.012

M3 - Article

C2 - 23994017

SN - 0303-7207

VL - 382

SP - 460

EP - 465

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

IS - 1

ER -