Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method

EAM Calvier; EHJ Krekels; TN Johnson; A Rostami-Hodjegan; Dick Tibboel; Catherijne Knibbe

doi:10.1208/s12248-019-0295-0

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method

EAM Calvier
, EHJ Krekels
, TN Johnson
, A Rostami-Hodjegan
, Dick Tibboel
, Catherijne Knibbe

Intensive Care

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

31 Downloads (Pure)

Original language	Undefined/Unknown
Article number	Unsp 38
Journal	AAPS Journal
Volume	21
Issue number	3
DOIs	https://doi.org/10.1208/s12248-019-0295-0
Publication status	Published - 2019

Research programs

EMC OR-01

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10.1208/s12248-019-0295-0

Repub_116098_O-A.pdfFinal published version, 1.43 MB

http://hdl.handle.net/1765/116098

Cite this

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title = "Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method",

author = "EAM Calvier and EHJ Krekels and TN Johnson and A Rostami-Hodjegan and Dick Tibboel and Catherijne Knibbe",

year = "2019",

doi = "10.1208/s12248-019-0295-0",

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AU - Calvier, EAM

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AU - Johnson, TN

AU - Rostami-Hodjegan, A

AU - Tibboel, Dick

AU - Knibbe, Catherijne

PY - 2019

Y1 - 2019

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SN - 1550-7416

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JO - AAPS Journal

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M1 - Unsp 38

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