Scheuermann Disease Evaluation of Radiological Criteria and Population Prevalence

AA Makurthou, Ling Oei - Oei, S El Saddy, Stephan Breda, Martha Castano Betancourt, Bert Hofman, Joyce van Meurs, André Uitterlinden, Fernando Rivadeneira, Edwin Oei

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)


Study Design. Observational population-based study. Objective. To determine the prevalence of radiographical Scheuermann disease in a Dutch population and evaluate the consistency of diagnostic criteria. Summary of Background Data. Scheuermann disease is a form of osteochondrosis characterized by increased posterior rounding of the thoracic spine with structural vertebral deformity. Different expert opinion-based radiological criteria exist, yet these have not been validated. The prevalence in the general population reported ranged from 1% to 10%. Methods. Lateral spine radiographs of 2753 Rotterdam Study participants (aged 45-89 yr) were assessed for Scheuermann disease using Sorensen and Sachs' radiographical criteria in 2 phases. Cohen. statistics were calculated for interrater agreement. Prevalence estimates were calculated and sex differences were tested with Pearson. 2 test. We evaluated whether varying the kyphosis angle criterion would change the prevalence estimate. Results. A total of 677 (24.6%) individuals had endplate irregularities and 140 (5.1%) individuals had vertebral wedging. Abnormalities were significantly more prevalent among males (P < 0.05). The interrater agreement. statistics were 78.8% for vertebral wedging and 79.4% for endplate irregularity. A total of 127 individuals had both criteria, of which 111 had a kyphosis angle greater than 45, resulting in a prevalence of 4.0% (95% confi dence interval [CI]: 3.3%-4.7%). The disease prevalence w Conclusion. Our results revealed a prevalence of 4.0% of radiographical Scheuermann disease in Dutch individuals aged 45 years and older. Although there is no current " gold standard" for the radiographical definition, standardized scoring of independent features resulted in substantial interobserver agreement, and different applications of diagnostic criteria did not signifi cantly alter the classification.
Original languageUndefined/Unknown
Pages (from-to)1690-1694
Number of pages5
Issue number19
Publication statusPublished - 2013

Research programs

  • EMC NIHES-03-30-01

Cite this