Screening and Early Detection of Lung Cancer

SC Westeinde, RJ Klaveren

Research output: Contribution to journalArticleAcademic

53 Citations (Scopus)

Abstract

Lung cancer with an estimated 342,000 deaths in 2008 (20% of total) is the most common cause of death from cancer, followed by colorectal cancer (12%), breast cancer (8%), and stomach cancer (7%) in Europe. In former smokers, the absolute lung cancer risk remains higher than in never-smokers; these data therefore call for effective secondary preventive measures for lung cancer in addition to smoking cessation programs. This review presents and discusses the most recent advances in the early detection and screening of lung cancer. An overview of randomized controlled computerized tomography-screening trials is given, and the role of bronchoscopy and new techniques is discussed. Finally, the approach of (noninvasive) biomarker testing in the blood, exhaled breath, sputum, and bronchoscopic specimen is reviewed.
Original languageUndefined/Unknown
Pages (from-to)3-10
Number of pages8
JournalCancer Journal
Volume17
Issue number1
DOIs
Publication statusPublished - 2011

Research programs

  • EMC MM-04-42-02

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