Segmentation of the Outer Vessel Wall of the Common Carotid Artery in CTA

Danijela Vukadinovic, Theo van Walsum, Rashindra Manniesing, Sietske Rozie, Krijn Hameeteman, Thomas Weert, Aad van der Lugt, Wiro Niessen

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42 Citations (Scopus)


A novel method is presented for carotid artery vessel wall segmentation in computed tomography angiography (CTA) data. First the carotid lumen is semi-automatically segmented using a level set approach initialized with three seed points. Subsequently, calcium regions located within the vessel wall are automatically detected and classified using multiple features in a GentleBoost framework. Calcium regions segmentation is used to improve localization of the outer vessel wall because it is an easier task than direct outer vessel wall segmentation. In a third step, pixels outside the lumen area are classified as vessel wall or background, using the same GentleBoost framework with a different set of image features. Finally, a 2-D ellipse shape deformable model is fitted to a cost image derived from both the calcium and vessel wall classifications. The method has been validated on a dataset of 60 CTA images. The experimental results show that the accuracy of the method is comparable to the interobserver variability.
Original languageUndefined/Unknown
Pages (from-to)65-76
Number of pages12
JournalIEEE Transactions on Medical Imaging
Issue number1
Publication statusPublished - 2010

Research programs

  • EMC COEUR-09
  • EMC NIHES-03-30-01
  • EMC NIHES-03-30-03

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