Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

J Bousquet; JM Anto; P Demoly; HJ Schunemann; A Togias; M Akdis; C Auffray; C Bachert; T Bieber; PJ Bousquet; KH Carlsen; TB Casale; AA Cruz; T Keil; KCL Carlsen; M Maurer; K Ohta; NG Papadopoulos; MR Rodriguez; B Samolinski; I Agache; A Andrianarisoa; CS Ang; I Annesi-Maesano; F Ballester; CE Baena-Cagnani; X Basagana; ED Bateman; EH Bel; A Bedbrook; B Beghe; M Beji; A Ben Kheder; M Benet; KS Bennoor; KC Bergmann; F Berrissoul; CB Jensen; ER Bleecker; S Bonini; AL Boner; LP Boulet; CE Brightling; JL Brozek; A Bush; WW Busse; PAM Camargos; GW Canonica; W Carr; A Cesario; YZ Chen; AM Chiriac; DJ Costa; L Cox; A Custovic; R Dahl; U Darsow; T Didi; WK Dolen; H Douagui; R Dubakiene; A El-Meziane; JA Fonseca; WJ Fokkens; E Fthenou; A Gamkrelidze; J Garcia-Aymerich; Roy Gerth van Wijk; E Gimeno-Santos; S Guerra; T Haahtela; H Haddad; PW Hellings; B Hellquist-Dahl; C Hohmann; P Howarth; JO Hourihane; M Humbert; B Jacquemin; J Just; O Kalayci; MA Kaliner; F Kauffmann; M Kerkhof; G Khayat; BK N'Goran; M Kogevinas; GH Koppelman; ML Kowalski; I Kull; P Kuna; D Larenas; I Lavi; LT Le; P Lieberman; B Lipworth; B Mahboub; MJ Makela; F Martin; FD Martinez; GD Marshall; A Mazon; E Melen; EO Meltzer; F Mihaltan; Y Mohammad; A Mohammadi; I Momas; M Morais-Almeida; J Mullol; A Muraro; R Naclerio; S Nafti; L Namazova-Baranova; MC (Martijn) Nawijn; TD Nyembue; S Oddie; RE O'Hehir; Y Okamoto; MP Orru; C Ozdemir; GS Ouedraogo; S Palkonen; P Panzner; G Passalacqua; R Pawankar; B Pigearias; I Pin; M Pinart; C Pison; TA Popov; D Porta; DS Postma; D Price; KF Rabe; J Ratomaharo; S Reitamo; D Rezagui; J Ring; R Roberts; J Roca; B Rogala; A Romano; J Rosado-Pinto; D Ryan; M Sanchez-Borges; GK Scadding; A (Aziz) Sheikh; FER Simons; V Siroux; PD Schmid-Grendelmeier; HA Smit; T Sooronbaev; RT Stein; PJ Sterk; J Sunyer; I Terreehorst; E Toskala; Y Tremblay; R Valenta; D Valeyre; O Vandenplas; C van Weel; M Vassilaki; R Varraso; G Viegi; DY Wang; M Wickman; D Williams; S Wohrl; J Wright; A Yorgancioglu; OM Yusuf; HJ Zar; ME Zernotti; M Zidarn; N Zhong; T Zuberbier

doi:10.1159/000332924

Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

J Bousquet, JM Anto, P Demoly, HJ Schunemann, A Togias, M Akdis, C Auffray, C Bachert, T Bieber, PJ Bousquet, KH Carlsen, TB Casale, AA Cruz, T Keil, KCL Carlsen, M Maurer, K Ohta, NG Papadopoulos, MR Rodriguez, B SamolinskiI Agache, A Andrianarisoa, CS Ang, I Annesi-Maesano, F Ballester, CE Baena-Cagnani, X Basagana, ED Bateman, EH Bel, A Bedbrook, B Beghe, M Beji, A Ben Kheder, M Benet, KS Bennoor, KC Bergmann, F Berrissoul, CB Jensen, ER Bleecker, S Bonini, AL Boner, LP Boulet, CE Brightling, JL Brozek, A Bush, WW Busse, PAM Camargos, GW Canonica, W Carr, A Cesario, YZ Chen, AM Chiriac, DJ Costa, L Cox, A Custovic, R Dahl, U Darsow, T Didi, WK Dolen, H Douagui, R Dubakiene, A El-Meziane, JA Fonseca, WJ Fokkens, E Fthenou, A Gamkrelidze, J Garcia-Aymerich, Roy Gerth van Wijk, E Gimeno-Santos, S Guerra, T Haahtela, H Haddad, PW Hellings, B Hellquist-Dahl, C Hohmann, P Howarth, JO Hourihane, M Humbert, B Jacquemin, J Just, O Kalayci, MA Kaliner, F Kauffmann, M Kerkhof, G Khayat, BK N'Goran, M Kogevinas, GH Koppelman, ML Kowalski, I Kull, P Kuna, D Larenas, I Lavi, LT Le, P Lieberman, B Lipworth, B Mahboub, MJ Makela, F Martin, FD Martinez, GD Marshall, A Mazon, E Melen, EO Meltzer, F Mihaltan, Y Mohammad, A Mohammadi, I Momas, M Morais-Almeida, J Mullol, A Muraro, R Naclerio, S Nafti, L Namazova-Baranova, MC (Martijn) Nawijn, TD Nyembue, S Oddie, RE O'Hehir, Y Okamoto, MP Orru, C Ozdemir, GS Ouedraogo, S Palkonen, P Panzner, G Passalacqua, R Pawankar, B Pigearias, I Pin, M Pinart, C Pison, TA Popov, D Porta, DS Postma, D Price, KF Rabe, J Ratomaharo, S Reitamo, D Rezagui, J Ring, R Roberts, J Roca, B Rogala, A Romano, J Rosado-Pinto, D Ryan, M Sanchez-Borges, GK Scadding, A (Aziz) Sheikh, FER Simons, V Siroux, PD Schmid-Grendelmeier, HA Smit, T Sooronbaev, RT Stein, PJ Sterk, J Sunyer, I Terreehorst, E Toskala, Y Tremblay, R Valenta, D Valeyre, O Vandenplas, C van Weel, M Vassilaki, R Varraso, G Viegi, DY Wang, M Wickman, D Williams, S Wohrl, J Wright, A Yorgancioglu, OM Yusuf, HJ Zar, ME Zernotti, M Zidarn, N Zhong, T Zuberbier

Research output: Contribution to journal › Article › Academic › peer-review

77 Citations (Scopus)

Abstract

Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

Original language	Undefined/Unknown
Pages (from-to)	216-231
Number of pages	16
Journal	International Archives of Allergy and Immunology
Volume	158
Issue number	3
DOIs	https://doi.org/10.1159/000332924
Publication status	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000332924

http://hdl.handle.net/1765/62525

Cite this

Bousquet, J., Anto, JM., Demoly, P., Schunemann, HJ., Togias, A., Akdis, M., Auffray, C., Bachert, C., Bieber, T., Bousquet, PJ., Carlsen, KH., Casale, TB., Cruz, AA., Keil, T., Carlsen, KCL., Maurer, M., Ohta, K., Papadopoulos, NG., Rodriguez, MR., ... Zuberbier, T. (2012). Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper. International Archives of Allergy and Immunology, 158(3), 216-231. https://doi.org/10.1159/000332924

@article{80abfc19df1e4e8b818d51606371823e,

title = "Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper",

abstract = "Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel",

author = "J Bousquet and JM Anto and P Demoly and HJ Schunemann and A Togias and M Akdis and C Auffray and C Bachert and T Bieber and PJ Bousquet and KH Carlsen and TB Casale and AA Cruz and T Keil and KCL Carlsen and M Maurer and K Ohta and NG Papadopoulos and MR Rodriguez and B Samolinski and I Agache and A Andrianarisoa and CS Ang and I Annesi-Maesano and F Ballester and CE Baena-Cagnani and X Basagana and ED Bateman and EH Bel and A Bedbrook and B Beghe and M Beji and {Ben Kheder}, A and M Benet and KS Bennoor and KC Bergmann and F Berrissoul and CB Jensen and ER Bleecker and S Bonini and AL Boner and LP Boulet and CE Brightling and JL Brozek and A Bush and WW Busse and PAM Camargos and GW Canonica and W Carr and A Cesario and YZ Chen and AM Chiriac and DJ Costa and L Cox and A Custovic and R Dahl and U Darsow and T Didi and WK Dolen and H Douagui and R Dubakiene and A El-Meziane and JA Fonseca and WJ Fokkens and E Fthenou and A Gamkrelidze and J Garcia-Aymerich and {Gerth van Wijk}, Roy and E Gimeno-Santos and S Guerra and T Haahtela and H Haddad and PW Hellings and B Hellquist-Dahl and C Hohmann and P Howarth and JO Hourihane and M Humbert and B Jacquemin and J Just and O Kalayci and MA Kaliner and F Kauffmann and M Kerkhof and G Khayat and BK N'Goran and M Kogevinas and GH Koppelman and ML Kowalski and I Kull and P Kuna and D Larenas and I Lavi and LT Le and P Lieberman and B Lipworth and B Mahboub and MJ Makela and F Martin and FD Martinez and GD Marshall and A Mazon and E Melen and EO Meltzer and F Mihaltan and Y Mohammad and A Mohammadi and I Momas and M Morais-Almeida and J Mullol and A Muraro and R Naclerio and S Nafti and L Namazova-Baranova and Nawijn, {MC (Martijn)} and TD Nyembue and S Oddie and RE O'Hehir and Y Okamoto and MP Orru and C Ozdemir and GS Ouedraogo and S Palkonen and P Panzner and G Passalacqua and R Pawankar and B Pigearias and I Pin and M Pinart and C Pison and TA Popov and D Porta and DS Postma and D Price and KF Rabe and J Ratomaharo and S Reitamo and D Rezagui and J Ring and R Roberts and J Roca and B Rogala and A Romano and J Rosado-Pinto and D Ryan and M Sanchez-Borges and GK Scadding and Sheikh, {A (Aziz)} and FER Simons and V Siroux and PD Schmid-Grendelmeier and HA Smit and T Sooronbaev and RT Stein and PJ Sterk and J Sunyer and I Terreehorst and E Toskala and Y Tremblay and R Valenta and D Valeyre and O Vandenplas and {van Weel}, C and M Vassilaki and R Varraso and G Viegi and DY Wang and M Wickman and D Williams and S Wohrl and J Wright and A Yorgancioglu and OM Yusuf and HJ Zar and ME Zernotti and M Zidarn and N Zhong and T Zuberbier",

year = "2012",

doi = "10.1159/000332924",

language = "Undefined/Unknown",

volume = "158",

pages = "216--231",

journal = "International Archives of Allergy and Immunology",

issn = "1018-2438",

publisher = "Karger",

number = "3",

}

Bousquet, J, Anto, JM, Demoly, P, Schunemann, HJ, Togias, A, Akdis, M, Auffray, C, Bachert, C, Bieber, T, Bousquet, PJ, Carlsen, KH, Casale, TB, Cruz, AA, Keil, T, Carlsen, KCL, Maurer, M, Ohta, K, Papadopoulos, NG, Rodriguez, MR, Samolinski, B, Agache, I, Andrianarisoa, A, Ang, CS, Annesi-Maesano, I, Ballester, F, Baena-Cagnani, CE, Basagana, X, Bateman, ED, Bel, EH, Bedbrook, A, Beghe, B, Beji, M, Ben Kheder, A, Benet, M, Bennoor, KS, Bergmann, KC, Berrissoul, F, Jensen, CB, Bleecker, ER, Bonini, S, Boner, AL, Boulet, LP, Brightling, CE, Brozek, JL, Bush, A, Busse, WW, Camargos, PAM, Canonica, GW, Carr, W, Cesario, A, Chen, YZ, Chiriac, AM, Costa, DJ, Cox, L, Custovic, A, Dahl, R, Darsow, U, Didi, T, Dolen, WK, Douagui, H, Dubakiene, R, El-Meziane, A, Fonseca, JA, Fokkens, WJ, Fthenou, E, Gamkrelidze, A, Garcia-Aymerich, J, Gerth van Wijk, R, Gimeno-Santos, E, Guerra, S, Haahtela, T, Haddad, H, Hellings, PW, Hellquist-Dahl, B, Hohmann, C, Howarth, P, Hourihane, JO, Humbert, M, Jacquemin, B, Just, J, Kalayci, O, Kaliner, MA, Kauffmann, F, Kerkhof, M, Khayat, G, N'Goran, BK, Kogevinas, M, Koppelman, GH, Kowalski, ML, Kull, I, Kuna, P, Larenas, D, Lavi, I, Le, LT, Lieberman, P, Lipworth, B, Mahboub, B, Makela, MJ, Martin, F, Martinez, FD, Marshall, GD, Mazon, A, Melen, E, Meltzer, EO, Mihaltan, F, Mohammad, Y, Mohammadi, A, Momas, I, Morais-Almeida, M, Mullol, J, Muraro, A, Naclerio, R, Nafti, S, Namazova-Baranova, L, Nawijn, MC, Nyembue, TD, Oddie, S, O'Hehir, RE, Okamoto, Y, Orru, MP, Ozdemir, C, Ouedraogo, GS, Palkonen, S, Panzner, P, Passalacqua, G, Pawankar, R, Pigearias, B, Pin, I, Pinart, M, Pison, C, Popov, TA, Porta, D, Postma, DS, Price, D, Rabe, KF, Ratomaharo, J, Reitamo, S, Rezagui, D, Ring, J, Roberts, R, Roca, J, Rogala, B, Romano, A, Rosado-Pinto, J, Ryan, D, Sanchez-Borges, M, Scadding, GK, Sheikh, A, Simons, FER, Siroux, V, Schmid-Grendelmeier, PD, Smit, HA, Sooronbaev, T, Stein, RT, Sterk, PJ, Sunyer, J, Terreehorst, I, Toskala, E, Tremblay, Y, Valenta, R, Valeyre, D, Vandenplas, O, van Weel, C, Vassilaki, M, Varraso, R, Viegi, G, Wang, DY, Wickman, M, Williams, D, Wohrl, S, Wright, J, Yorgancioglu, A, Yusuf, OM, Zar, HJ, Zernotti, ME, Zidarn, M, Zhong, N & Zuberbier, T 2012, 'Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper', International Archives of Allergy and Immunology, vol. 158, no. 3, pp. 216-231. https://doi.org/10.1159/000332924

TY - JOUR

T1 - Severe Chronic Allergic (and Related) Diseases: A Uniform Approach - A MeDALL - GA(2)LEN - ARIA Position Paper

AU - Bousquet, J

AU - Anto, JM

AU - Demoly, P

AU - Schunemann, HJ

AU - Togias, A

AU - Akdis, M

AU - Auffray, C

AU - Bachert, C

AU - Bieber, T

AU - Bousquet, PJ

AU - Carlsen, KH

AU - Casale, TB

AU - Cruz, AA

AU - Keil, T

AU - Carlsen, KCL

AU - Maurer, M

AU - Ohta, K

AU - Papadopoulos, NG

AU - Rodriguez, MR

AU - Samolinski, B

AU - Agache, I

AU - Andrianarisoa, A

AU - Ang, CS

AU - Annesi-Maesano, I

AU - Ballester, F

AU - Baena-Cagnani, CE

AU - Basagana, X

AU - Bateman, ED

AU - Bel, EH

AU - Bedbrook, A

AU - Beghe, B

AU - Beji, M

AU - Ben Kheder, A

AU - Benet, M

AU - Bennoor, KS

AU - Bergmann, KC

AU - Berrissoul, F

AU - Jensen, CB

AU - Bleecker, ER

AU - Bonini, S

AU - Boner, AL

AU - Boulet, LP

AU - Brightling, CE

AU - Brozek, JL

AU - Bush, A

AU - Busse, WW

AU - Camargos, PAM

AU - Canonica, GW

AU - Carr, W

AU - Cesario, A

AU - Chen, YZ

AU - Chiriac, AM

AU - Costa, DJ

AU - Cox, L

AU - Custovic, A

AU - Dahl, R

AU - Darsow, U

AU - Didi, T

AU - Dolen, WK

AU - Douagui, H

AU - Dubakiene, R

AU - El-Meziane, A

AU - Fonseca, JA

AU - Fokkens, WJ

AU - Fthenou, E

AU - Gamkrelidze, A

AU - Garcia-Aymerich, J

AU - Gerth van Wijk, Roy

AU - Gimeno-Santos, E

AU - Guerra, S

AU - Haahtela, T

AU - Haddad, H

AU - Hellings, PW

AU - Hellquist-Dahl, B

AU - Hohmann, C

AU - Howarth, P

AU - Hourihane, JO

AU - Humbert, M

AU - Jacquemin, B

AU - Just, J

AU - Kalayci, O

AU - Kaliner, MA

AU - Kauffmann, F

AU - Kerkhof, M

AU - Khayat, G

AU - N'Goran, BK

AU - Kogevinas, M

AU - Koppelman, GH

AU - Kowalski, ML

AU - Kull, I

AU - Kuna, P

AU - Larenas, D

AU - Lavi, I

AU - Le, LT

AU - Lieberman, P

AU - Lipworth, B

AU - Mahboub, B

AU - Makela, MJ

AU - Martin, F

AU - Martinez, FD

AU - Marshall, GD

AU - Mazon, A

AU - Melen, E

AU - Meltzer, EO

AU - Mihaltan, F

AU - Mohammad, Y

AU - Mohammadi, A

AU - Momas, I

AU - Morais-Almeida, M

AU - Mullol, J

AU - Muraro, A

AU - Naclerio, R

AU - Nafti, S

AU - Namazova-Baranova, L

AU - Nawijn, MC (Martijn)

AU - Nyembue, TD

AU - Oddie, S

AU - O'Hehir, RE

AU - Okamoto, Y

AU - Orru, MP

AU - Ozdemir, C

AU - Ouedraogo, GS

AU - Palkonen, S

AU - Panzner, P

AU - Passalacqua, G

AU - Pawankar, R

AU - Pigearias, B

AU - Pin, I

AU - Pinart, M

AU - Pison, C

AU - Popov, TA

AU - Porta, D

AU - Postma, DS

AU - Price, D

AU - Rabe, KF

AU - Ratomaharo, J

AU - Reitamo, S

AU - Rezagui, D

AU - Ring, J

AU - Roberts, R

AU - Roca, J

AU - Rogala, B

AU - Romano, A

AU - Rosado-Pinto, J

AU - Ryan, D

AU - Sanchez-Borges, M

AU - Scadding, GK

AU - Sheikh, A (Aziz)

AU - Simons, FER

AU - Siroux, V

AU - Schmid-Grendelmeier, PD

AU - Smit, HA

AU - Sooronbaev, T

AU - Stein, RT

AU - Sterk, PJ

AU - Sunyer, J

AU - Terreehorst, I

AU - Toskala, E

AU - Tremblay, Y

AU - Valenta, R

AU - Valeyre, D

AU - Vandenplas, O

AU - van Weel, C

AU - Vassilaki, M

AU - Varraso, R

AU - Viegi, G

AU - Wang, DY

AU - Wickman, M

AU - Williams, D

AU - Wohrl, S

AU - Wright, J

AU - Yorgancioglu, A

AU - Yusuf, OM

AU - Zar, HJ

AU - Zernotti, ME

AU - Zidarn, M

AU - Zhong, N

AU - Zuberbier, T

PY - 2012

Y1 - 2012

N2 - Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

AB - Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in order to have a uniform definition of severity, control and risk, usable in most situations. It is based on the appropriate diagnosis, availability and accessibility of treatments, treatment responsiveness and associated factors such as comorbidities and risk factors. This uniform definition will allow a better definition of the phenotypes of severe allergic (and related) diseases for clinical practice, research (including epidemiology), public health purposes, education and the discovery of novel therapies. Copyright (C) 2012 S. Karger AG, Basel

U2 - 10.1159/000332924

DO - 10.1159/000332924

M3 - Article

VL - 158

SP - 216

EP - 231

JO - International Archives of Allergy and Immunology

JF - International Archives of Allergy and Immunology

SN - 1018-2438

IS - 3

ER -