Sex-Related Trends in Mortality in Hospitalized Men and Women After Myocardial Infarction Between 1985 and 2008 Equal Benefit for Women and Men

Sjoerd Nauta, Jaap Deckers, Ron van Domburg, Martijn Akkerhuis

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33 Citations (Scopus)


Background-We aimed to study sex-related differences in temporal trends in short-and long-term mortality from 1985 to 2008 in patients hospitalized for acute myocardial infarction. Methods and Results-We included a total of 14 434 consecutive patients admitted to our intensive coronary care unit between 1985 and 2008 for myocardial infarction. A total of 4028 patients (28%) were women. Women were more likely to present with a higher risk profile and were equally likely to receive pharmacological and invasive reperfusion therapy compared with men. Women had a higher unadjusted mortality rate at 30 days (odds ratio, 1.3; 95% confidence interval, 1.1-1.5) and during 20 years Conclusions-The fact that adjusted mortality rates for men and women treated for myocardial infarction in an intensive coronary care unit were similar and declined markedly over a 24-year period suggests that both sexes benefit from the evidence-based therapies that have been developed and implemented during this time period. (Circulation. 2012;126:2184-2189.)
Original languageUndefined/Unknown
Pages (from-to)2184-2189
Number of pages6
Issue number18
Publication statusPublished - 2012

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