Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study

Laurens A. van Kleef*, Tian Xiao, M. Arfan Ikram, Kamran Ikram, Robert J. de Knegt

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)


Fatty liver disease was not associated with Parkinsonism or Parkinson's disease in an elderly European population, the Rotterdam Study, (n = 8.848), neither in men nor women. Results were consistent either using non-alcoholic fatty liver disease (NAFLD) or metabolic-dysfunction associated fatty liver disease (MAFLD) as exposure defined by either fatty liver index (FLI) or ultrasound.

Original languageEnglish
Article number105233
JournalParkinsonism and Related Disorders
Early online date30 Nov 2022
Publication statusPublished - 1 Jan 2023

Bibliographical note

Funding Information: The Rotterdam Study is funded by Erasmus Medical Center and Erasmus University, Rotterdam , Netherlands Organization for the Health Research and Development (ZonMw) , t he Research institute for Diseases in the Elderly (Ride) , the Ministry of Education, Culture and Science, the Ministry for Health, Welfare and Sports , the European Commission (DG XII) and the Municipality of Rotterdam . Further funding was obtained through the Stichting Erasmus Trustfonds , grant number 97030.2021.101.430/057/RB . Financial support was also provided by the Foundation for Liver and Gastrointestinal Research, Rotterdam, the Netherlands . The funding sources did not influence study design, data collection, analysis and interpretation of the data, nor the writing of the report and decision to submit for publication.

Publisher Copyright: © 2022 Elsevier Ltd


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