Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study

Laurens A. van Kleef; Tian Xiao; M. Arfan Ikram; Kamran Ikram; Robert J. de Knegt

doi:10.1016/j.parkreldis.2022.105233

Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study

Laurens A. van Kleef^*, Tian Xiao, M. Arfan Ikram, Kamran Ikram, Robert J. de Knegt

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Fatty liver disease was not associated with Parkinsonism or Parkinson's disease in an elderly European population, the Rotterdam Study, (n = 8.848), neither in men nor women. Results were consistent either using non-alcoholic fatty liver disease (NAFLD) or metabolic-dysfunction associated fatty liver disease (MAFLD) as exposure defined by either fatty liver index (FLI) or ultrasound.

Original language	English
Article number	105233
Journal	Parkinsonism and Related Disorders
Volume	106
Early online date	30 Nov 2022
DOIs	https://doi.org/10.1016/j.parkreldis.2022.105233
Publication status	Published - 1 Jan 2023

Bibliographical note

Funding Information: The Rotterdam Study is funded by Erasmus Medical Center and Erasmus University, Rotterdam , Netherlands Organization for the Health Research and Development (ZonMw) , t he Research institute for Diseases in the Elderly (Ride) , the Ministry of Education, Culture and Science, the Ministry for Health, Welfare and Sports , the European Commission (DG XII) and the Municipality of Rotterdam . Further funding was obtained through the Stichting Erasmus Trustfonds , grant number 97030.2021.101.430/057/RB . Financial support was also provided by the Foundation for Liver and Gastrointestinal Research, Rotterdam, the Netherlands . The funding sources did not influence study design, data collection, analysis and interpretation of the data, nor the writing of the report and decision to submit for publication.

Publisher Copyright: © 2022 Elsevier Ltd

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title = "Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study",

abstract = "Fatty liver disease was not associated with Parkinsonism or Parkinson's disease in an elderly European population, the Rotterdam Study, (n = 8.848), neither in men nor women. Results were consistent either using non-alcoholic fatty liver disease (NAFLD) or metabolic-dysfunction associated fatty liver disease (MAFLD) as exposure defined by either fatty liver index (FLI) or ultrasound.",

author = "{van Kleef}, {Laurens A.} and Tian Xiao and Ikram, {M. Arfan} and Kamran Ikram and {de Knegt}, {Robert J.}",

note = "Funding Information: The Rotterdam Study is funded by Erasmus Medical Center and Erasmus University, Rotterdam , Netherlands Organization for the Health Research and Development (ZonMw) , t he Research institute for Diseases in the Elderly (Ride) , the Ministry of Education, Culture and Science, the Ministry for Health, Welfare and Sports , the European Commission (DG XII) and the Municipality of Rotterdam . Further funding was obtained through the Stichting Erasmus Trustfonds , grant number 97030.2021.101.430/057/RB . Financial support was also provided by the Foundation for Liver and Gastrointestinal Research, Rotterdam, the Netherlands . The funding sources did not influence study design, data collection, analysis and interpretation of the data, nor the writing of the report and decision to submit for publication. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

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AU - van Kleef, Laurens A.

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AU - Ikram, M. Arfan

AU - Ikram, Kamran

AU - de Knegt, Robert J.

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Sex-stratified associations between fatty liver disease and Parkinson's disease: The Rotterdam study

Abstract

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