Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

JC Randall; TW Winkler; Z Kutalik; SI Berndt; AU Jackson; KL Monda; TO Kilpelainen; T Esko; R Magi; SX Li; T Workalemahu; MF Feitosa; DC Croteau-Chonka; FR Day; T Fall; T Ferreira; S Gustafsson; AE Locke; I Mathieson; A Scherag; S Vedantam; AR Wood; LM Liang; V Steinthorsdottir; G Thorleifsson; ET Dermitzakis; AS Dimas; F Karpe; JL Min; G Nicholson; DJ Clegg; T Person; JP Krohn; S Bauer; C Buechler; K Eisinger; A Bonnefond; P Froguel; JJ (Jouke Jan) Hottenga; I Prokopenko; LL Waite; TB Harris; AV Smith; AR Shuldiner; WL McArdle; MJ Caulfield; PB Munroe; H Gronberg; YDI Chen; G (Guo) Li; JS Beckmann; T Johnson; U Thorsteinsdottir; M Teder-Laving; KT Khaw; NJ Wareham; JH Zhao; Najaf Amin; Ben Oostra; AT Kraja; MA Province; LA Cupples; NL Heard-Costa; J Kaprio; S Ripatti; I Surakka; FS Collins; J Saramies; J Tuomilehto; A Jula; V Salomaa; J Erdmann; C Hengstenberg; C Loley; H Schunkert; C Lamina; HE Wichmann; E Albrecht; C Gieger; AA Hicks; A Johansson; PP Pramstaller; S Kathiresan; EK Speliotes; B Penninx; AL Hartikainen; MR Jarvelin; U Gyllensten; DI Boomsma; H Campbell; JF Wilson; SJ Chanock; M Farrall; A Goel; C Medina-Gomez; Fernando Rivadeneira; Karol Estrada Gil; André Uitterlinden; Bert Hofman; M.C. Zillikens; Mariska Heijer; LA Kiemeney; A del Maschio; P Hall; J Tyrer; A Teumer; H Volzke; P Kovacs; A Tonjes; M Mangino; TD Spector; C Hayward; I Rudan; AS Hall; NJ Samani; AP Attwood; JG Sambrook; J Hung; LJ Palmer; ML Lokki; J Sinisalo; G Boucher; H Huikuri; M Lorentzon; C Ohlsson; N Eklund; JG Eriksson; C Barlassina; C Rivolta; IM (Ilja) Nolte; H Snieder; MM (Melanie) van der Klauw; JV van Vliet-Ostaptchouk; PV Gejman; JX Shi; KB Jacobs; ZM Wang; SJL Bakker; IM Leach; G Navis; P van der Harst; NG Martin; SE Medland; GW Montgomery; Jiaqi Yang; DI Chasman; PM Ridker; LM Rose; T Lehtimaki; O Raitakari; D Absher; C Iribarren; H Basart; KG Hovingh; E Hypponen; C Power; D Anderson; JP Beilby; JN Hui; J Jolley; H Sager; SR Bornstein; PEH Schwarz; K Kristiansson; M Perola; J Lindstrom; AJ Swift; M Uusitupa; M Atalay; TA Lakka; R Rauramaa; JL Bolton; G Fowkes; RM Fraser; JF Price; K (Kirsten) Fischer; K KrjutAikov; A Metspalu; E Mihailov; C Langenberg; JA Luan; KK Ong; PS Chines; SM Keinanen-Kiukaanniemi; TE Saaristo; S Edkins; PW Franks; G Hallmans; D Shungin; AD Morris; CNA Palmer; R Erbel; S Moebus; MM Nothen; S Pechlivanis; K Hveem; N Narisu; A Hamsten; SE Humphries; RJ Strawbridge; E Tremoli; H Grallert; B Thorand; T Illig; W Koenig; M Muller-Nurasyid; A Peters; BO Boehm; ME Kleber; W Marz; BR Winkelmann; J Kuusisto; M Laakso; D Arveiler; G Cesana; K Kuulasmaa; J Virtamo; JWG Yarnell; D Kuh; A Wong; L Lind; U de Faire; B Gigante; PKE Magnusson; NL Pedersen; G Dedoussis; M Dimitriou; G Kolovou; S Kanoni; K Stirrups; LL Bonnycastle; I Njolstad; T Wilsgaard; A Ganna; E Rehnberg; A Hingorani; M Kivimaki; M Kumari; TL Assimes; IS Barroso; M Boehnke; IB Borecki; P Deloukas; CS Fox; T Frayling; LC Groop; T Haritunians; D Hunter; E Ingelsson; R Kaplan; KL Mohlke; JR O'Connell; D Schlessinger; DP Strachan; K Stefansson; Cornelia Duijn; GR Abecasis; MI McCarthy; JN Hirschhorn; L Qi; RJF Loos; CM Lindgren; KE North; IM Heid

doi:10.1371/journal.pgen.1003500

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, TO Kilpelainen, T Esko, R Magi, SX Li, T Workalemahu, MF Feitosa, DC Croteau-Chonka, FR Day, T Fall, T Ferreira, S Gustafsson, AE Locke, I Mathieson, A ScheragS Vedantam, AR Wood, LM Liang, V Steinthorsdottir, G Thorleifsson, ET Dermitzakis, AS Dimas, F Karpe, JL Min, G Nicholson, DJ Clegg, T Person, JP Krohn, S Bauer, C Buechler, K Eisinger, A Bonnefond, P Froguel, JJ (Jouke Jan) Hottenga, I Prokopenko, LL Waite, TB Harris, AV Smith, AR Shuldiner, WL McArdle, MJ Caulfield, PB Munroe, H Gronberg, YDI Chen, G (Guo) Li, JS Beckmann, T Johnson, U Thorsteinsdottir, M Teder-Laving, KT Khaw, NJ Wareham, JH Zhao, Najaf Amin, Ben Oostra, AT Kraja, MA Province, LA Cupples, NL Heard-Costa, J Kaprio, S Ripatti, I Surakka, FS Collins, J Saramies, J Tuomilehto, A Jula, V Salomaa, J Erdmann, C Hengstenberg, C Loley, H Schunkert, C Lamina, HE Wichmann, E Albrecht, C Gieger, AA Hicks, A Johansson, PP Pramstaller, S Kathiresan, EK Speliotes, B Penninx, AL Hartikainen, MR Jarvelin, U Gyllensten, DI Boomsma, H Campbell, JF Wilson, SJ Chanock, M Farrall, A Goel, C Medina-Gomez, Fernando Rivadeneira, Karol Estrada Gil, André Uitterlinden, Bert Hofman, M.C. Zillikens, Mariska Heijer, LA Kiemeney, A del Maschio, P Hall, J Tyrer, A Teumer, H Volzke, P Kovacs, A Tonjes, M Mangino, TD Spector, C Hayward, I Rudan, AS Hall, NJ Samani, AP Attwood, JG Sambrook, J Hung, LJ Palmer, ML Lokki, J Sinisalo, G Boucher, H Huikuri, M Lorentzon, C Ohlsson, N Eklund, JG Eriksson, C Barlassina, C Rivolta, IM (Ilja) Nolte, H Snieder, MM (Melanie) van der Klauw, JV van Vliet-Ostaptchouk, PV Gejman, JX Shi, KB Jacobs, ZM Wang, SJL Bakker, IM Leach, G Navis, P van der Harst, NG Martin, SE Medland, GW Montgomery, Jiaqi Yang, DI Chasman, PM Ridker, LM Rose, T Lehtimaki, O Raitakari, D Absher, C Iribarren, H Basart, KG Hovingh, E Hypponen, C Power, D Anderson, JP Beilby, JN Hui, J Jolley, H Sager, SR Bornstein, PEH Schwarz, K Kristiansson, M Perola, J Lindstrom, AJ Swift, M Uusitupa, M Atalay, TA Lakka, R Rauramaa, JL Bolton, G Fowkes, RM Fraser, JF Price, K (Kirsten) Fischer, K KrjutAikov, A Metspalu, E Mihailov, C Langenberg, JA Luan, KK Ong, PS Chines, SM Keinanen-Kiukaanniemi, TE Saaristo, S Edkins, PW Franks, G Hallmans, D Shungin, AD Morris, CNA Palmer, R Erbel, S Moebus, MM Nothen, S Pechlivanis, K Hveem, N Narisu, A Hamsten, SE Humphries, RJ Strawbridge, E Tremoli, H Grallert, B Thorand, T Illig, W Koenig, M Muller-Nurasyid, A Peters, BO Boehm, ME Kleber, W Marz, BR Winkelmann, J Kuusisto, M Laakso, D Arveiler, G Cesana, K Kuulasmaa, J Virtamo, JWG Yarnell, D Kuh, A Wong, L Lind, U de Faire, B Gigante, PKE Magnusson, NL Pedersen, G Dedoussis, M Dimitriou, G Kolovou, S Kanoni, K Stirrups, LL Bonnycastle, I Njolstad, T Wilsgaard, A Ganna, E Rehnberg, A Hingorani, M Kivimaki, M Kumari, TL Assimes, IS Barroso, M Boehnke, IB Borecki, P Deloukas, CS Fox, T Frayling, LC Groop, T Haritunians, D Hunter, E Ingelsson, R Kaplan, KL Mohlke, JR O'Connell, D Schlessinger, DP Strachan, K Stefansson, Cornelia Duijn, GR Abecasis, MI McCarthy, JN Hirschhorn, L Qi, RJF Loos, CM Lindgren, KE North, IM Heid

Research output: Contribution to journal › Article › Academic › peer-review

249 Citations (Scopus)

1 Downloads (Pure)

Original language	English
Journal	PLoS Genetics (print)
Volume	9
Issue number	6
DOIs	https://doi.org/10.1371/journal.pgen.1003500
Publication status	Published - 2013

Access to Document

10.1371/journal.pgen.1003500

REPUB_70673-OA.pdfFinal published version, 2.94 MB

http://hdl.handle.net/1765/70673

Cite this

Randall, JC., Winkler, TW., Kutalik, Z., Berndt, SI., Jackson, AU., Monda, KL., Kilpelainen, TO., Esko, T., Magi, R., Li, SX., Workalemahu, T., Feitosa, MF., Croteau-Chonka, DC., Day, FR., Fall, T., Ferreira, T., Gustafsson, S., Locke, AE., Mathieson, I., ... Heid, IM. (2013). Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics (print), 9(6). https://doi.org/10.1371/journal.pgen.1003500

Randall, JC ; Winkler, TW ; Kutalik, Z ; Berndt, SI ; Jackson, AU ; Monda, KL ; Kilpelainen, TO ; Esko, T ; Magi, R ; Li, SX ; Workalemahu, T ; Feitosa, MF ; Croteau-Chonka, DC ; Day, FR ; Fall, T ; Ferreira, T ; Gustafsson, S ; Locke, AE ; Mathieson, I ; Scherag, A ; Vedantam, S ; Wood, AR ; Liang, LM ; Steinthorsdottir, V ; Thorleifsson, G ; Dermitzakis, ET ; Dimas, AS ; Karpe, F ; Min, JL ; Nicholson, G ; Clegg, DJ ; Person, T ; Krohn, JP ; Bauer, S ; Buechler, C ; Eisinger, K ; Bonnefond, A ; Froguel, P ; Hottenga, JJ (Jouke Jan) ; Prokopenko, I ; Waite, LL ; Harris, TB ; Smith, AV ; Shuldiner, AR ; McArdle, WL ; Caulfield, MJ ; Munroe, PB ; Gronberg, H ; Chen, YDI ; Li, G (Guo) ; Beckmann, JS ; Johnson, T ; Thorsteinsdottir, U ; Teder-Laving, M ; Khaw, KT ; Wareham, NJ ; Zhao, JH ; Amin, Najaf ; Oostra, Ben ; Kraja, AT ; Province, MA ; Cupples, LA ; Heard-Costa, NL ; Kaprio, J ; Ripatti, S ; Surakka, I ; Collins, FS ; Saramies, J ; Tuomilehto, J ; Jula, A ; Salomaa, V ; Erdmann, J ; Hengstenberg, C ; Loley, C ; Schunkert, H ; Lamina, C ; Wichmann, HE ; Albrecht, E ; Gieger, C ; Hicks, AA ; Johansson, A ; Pramstaller, PP ; Kathiresan, S ; Speliotes, EK ; Penninx, B ; Hartikainen, AL ; Jarvelin, MR ; Gyllensten, U ; Boomsma, DI ; Campbell, H ; Wilson, JF ; Chanock, SJ ; Farrall, M ; Goel, A ; Medina-Gomez, C ; Rivadeneira, Fernando ; Estrada Gil, Karol ; Uitterlinden, André ; Hofman, Bert ; Zillikens, M.C. ; Heijer, Mariska ; Kiemeney, LA ; del Maschio, A ; Hall, P ; Tyrer, J ; Teumer, A ; Volzke, H ; Kovacs, P ; Tonjes, A ; Mangino, M ; Spector, TD ; Hayward, C ; Rudan, I ; Hall, AS ; Samani, NJ ; Attwood, AP ; Sambrook, JG ; Hung, J ; Palmer, LJ ; Lokki, ML ; Sinisalo, J ; Boucher, G ; Huikuri, H ; Lorentzon, M ; Ohlsson, C ; Eklund, N ; Eriksson, JG ; Barlassina, C ; Rivolta, C ; Nolte, IM (Ilja) ; Snieder, H ; van der Klauw, MM (Melanie) ; van Vliet-Ostaptchouk, JV ; Gejman, PV ; Shi, JX ; Jacobs, KB ; Wang, ZM ; Bakker, SJL ; Leach, IM ; Navis, G ; van der Harst, P ; Martin, NG ; Medland, SE ; Montgomery, GW ; Yang, Jiaqi ; Chasman, DI ; Ridker, PM ; Rose, LM ; Lehtimaki, T ; Raitakari, O ; Absher, D ; Iribarren, C ; Basart, H ; Hovingh, KG ; Hypponen, E ; Power, C ; Anderson, D ; Beilby, JP ; Hui, JN ; Jolley, J ; Sager, H ; Bornstein, SR ; Schwarz, PEH ; Kristiansson, K ; Perola, M ; Lindstrom, J ; Swift, AJ ; Uusitupa, M ; Atalay, M ; Lakka, TA ; Rauramaa, R ; Bolton, JL ; Fowkes, G ; Fraser, RM ; Price, JF ; Fischer, K (Kirsten) ; KrjutAikov, K ; Metspalu, A ; Mihailov, E ; Langenberg, C ; Luan, JA ; Ong, KK ; Chines, PS ; Keinanen-Kiukaanniemi, SM ; Saaristo, TE ; Edkins, S ; Franks, PW ; Hallmans, G ; Shungin, D ; Morris, AD ; Palmer, CNA ; Erbel, R ; Moebus, S ; Nothen, MM ; Pechlivanis, S ; Hveem, K ; Narisu, N ; Hamsten, A ; Humphries, SE ; Strawbridge, RJ ; Tremoli, E ; Grallert, H ; Thorand, B ; Illig, T ; Koenig, W ; Muller-Nurasyid, M ; Peters, A ; Boehm, BO ; Kleber, ME ; Marz, W ; Winkelmann, BR ; Kuusisto, J ; Laakso, M ; Arveiler, D ; Cesana, G ; Kuulasmaa, K ; Virtamo, J ; Yarnell, JWG ; Kuh, D ; Wong, A ; Lind, L ; de Faire, U ; Gigante, B ; Magnusson, PKE ; Pedersen, NL ; Dedoussis, G ; Dimitriou, M ; Kolovou, G ; Kanoni, S ; Stirrups, K ; Bonnycastle, LL ; Njolstad, I ; Wilsgaard, T ; Ganna, A ; Rehnberg, E ; Hingorani, A ; Kivimaki, M ; Kumari, M ; Assimes, TL ; Barroso, IS ; Boehnke, M ; Borecki, IB ; Deloukas, P ; Fox, CS ; Frayling, T ; Groop, LC ; Haritunians, T ; Hunter, D ; Ingelsson, E ; Kaplan, R ; Mohlke, KL ; O'Connell, JR ; Schlessinger, D ; Strachan, DP ; Stefansson, K ; Duijn, Cornelia ; Abecasis, GR ; McCarthy, MI ; Hirschhorn, JN ; Qi, L ; Loos, RJF ; Lindgren, CM ; North, KE ; Heid, IM. / Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. In: PLoS Genetics (print). 2013 ; Vol. 9, No. 6.

@article{924328156d074f6495a2e80f54409c11,

title = "Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits",

author = "JC Randall and TW Winkler and Z Kutalik and SI Berndt and AU Jackson and KL Monda and TO Kilpelainen and T Esko and R Magi and SX Li and T Workalemahu and MF Feitosa and DC Croteau-Chonka and FR Day and T Fall and T Ferreira and S Gustafsson and AE Locke and I Mathieson and A Scherag and S Vedantam and AR Wood and LM Liang and V Steinthorsdottir and G Thorleifsson and ET Dermitzakis and AS Dimas and F Karpe and JL Min and G Nicholson and DJ Clegg and T Person and JP Krohn and S Bauer and C Buechler and K Eisinger and A Bonnefond and P Froguel and Hottenga, {JJ (Jouke Jan)} and I Prokopenko and LL Waite and TB Harris and AV Smith and AR Shuldiner and WL McArdle and MJ Caulfield and PB Munroe and H Gronberg and YDI Chen and Li, {G (Guo)} and JS Beckmann and T Johnson and U Thorsteinsdottir and M Teder-Laving and KT Khaw and NJ Wareham and JH Zhao and Najaf Amin and Ben Oostra and AT Kraja and MA Province and LA Cupples and NL Heard-Costa and J Kaprio and S Ripatti and I Surakka and FS Collins and J Saramies and J Tuomilehto and A Jula and V Salomaa and J Erdmann and C Hengstenberg and C Loley and H Schunkert and C Lamina and HE Wichmann and E Albrecht and C Gieger and AA Hicks and A Johansson and PP Pramstaller and S Kathiresan and EK Speliotes and B Penninx and AL Hartikainen and MR Jarvelin and U Gyllensten and DI Boomsma and H Campbell and JF Wilson and SJ Chanock and M Farrall and A Goel and C Medina-Gomez and Fernando Rivadeneira and {Estrada Gil}, Karol and Andr{\'e} Uitterlinden and Bert Hofman and M.C. Zillikens and Mariska Heijer and LA Kiemeney and {del Maschio}, A and P Hall and J Tyrer and A Teumer and H Volzke and P Kovacs and A Tonjes and M Mangino and TD Spector and C Hayward and I Rudan and AS Hall and NJ Samani and AP Attwood and JG Sambrook and J Hung and LJ Palmer and ML Lokki and J Sinisalo and G Boucher and H Huikuri and M Lorentzon and C Ohlsson and N Eklund and JG Eriksson and C Barlassina and C Rivolta and Nolte, {IM (Ilja)} and H Snieder and {van der Klauw}, {MM (Melanie)} and {van Vliet-Ostaptchouk}, JV and PV Gejman and JX Shi and KB Jacobs and ZM Wang and SJL Bakker and IM Leach and G Navis and {van der Harst}, P and NG Martin and SE Medland and GW Montgomery and Jiaqi Yang and DI Chasman and PM Ridker and LM Rose and T Lehtimaki and O Raitakari and D Absher and C Iribarren and H Basart and KG Hovingh and E Hypponen and C Power and D Anderson and JP Beilby and JN Hui and J Jolley and H Sager and SR Bornstein and PEH Schwarz and K Kristiansson and M Perola and J Lindstrom and AJ Swift and M Uusitupa and M Atalay and TA Lakka and R Rauramaa and JL Bolton and G Fowkes and RM Fraser and JF Price and Fischer, {K (Kirsten)} and K KrjutAikov and A Metspalu and E Mihailov and C Langenberg and JA Luan and KK Ong and PS Chines and SM Keinanen-Kiukaanniemi and TE Saaristo and S Edkins and PW Franks and G Hallmans and D Shungin and AD Morris and CNA Palmer and R Erbel and S Moebus and MM Nothen and S Pechlivanis and K Hveem and N Narisu and A Hamsten and SE Humphries and RJ Strawbridge and E Tremoli and H Grallert and B Thorand and T Illig and W Koenig and M Muller-Nurasyid and A Peters and BO Boehm and ME Kleber and W Marz and BR Winkelmann and J Kuusisto and M Laakso and D Arveiler and G Cesana and K Kuulasmaa and J Virtamo and JWG Yarnell and D Kuh and A Wong and L Lind and {de Faire}, U and B Gigante and PKE Magnusson and NL Pedersen and G Dedoussis and M Dimitriou and G Kolovou and S Kanoni and K Stirrups and LL Bonnycastle and I Njolstad and T Wilsgaard and A Ganna and E Rehnberg and A Hingorani and M Kivimaki and M Kumari and TL Assimes and IS Barroso and M Boehnke and IB Borecki and P Deloukas and CS Fox and T Frayling and LC Groop and T Haritunians and D Hunter and E Ingelsson and R Kaplan and KL Mohlke and JR O'Connell and D Schlessinger and DP Strachan and K Stefansson and Cornelia Duijn and GR Abecasis and MI McCarthy and JN Hirschhorn and L Qi and RJF Loos and CM Lindgren and KE North and IM Heid",

year = "2013",

doi = "10.1371/journal.pgen.1003500",

language = "English",

volume = "9",

journal = "PLoS Genetics",

issn = "1553-7390",

publisher = "Public Library of Science",

number = "6",

}

Randall, JC, Winkler, TW, Kutalik, Z, Berndt, SI, Jackson, AU, Monda, KL, Kilpelainen, TO, Esko, T, Magi, R, Li, SX, Workalemahu, T, Feitosa, MF, Croteau-Chonka, DC, Day, FR, Fall, T, Ferreira, T, Gustafsson, S, Locke, AE, Mathieson, I, Scherag, A, Vedantam, S, Wood, AR, Liang, LM, Steinthorsdottir, V, Thorleifsson, G, Dermitzakis, ET, Dimas, AS, Karpe, F, Min, JL, Nicholson, G, Clegg, DJ, Person, T, Krohn, JP, Bauer, S, Buechler, C, Eisinger, K, Bonnefond, A, Froguel, P, Hottenga, JJ, Prokopenko, I, Waite, LL, Harris, TB, Smith, AV, Shuldiner, AR, McArdle, WL, Caulfield, MJ, Munroe, PB, Gronberg, H, Chen, YDI, Li, G, Beckmann, JS, Johnson, T, Thorsteinsdottir, U, Teder-Laving, M, Khaw, KT, Wareham, NJ, Zhao, JH, Amin, N, Oostra, B, Kraja, AT, Province, MA, Cupples, LA, Heard-Costa, NL, Kaprio, J, Ripatti, S, Surakka, I, Collins, FS, Saramies, J, Tuomilehto, J, Jula, A, Salomaa, V, Erdmann, J, Hengstenberg, C, Loley, C, Schunkert, H, Lamina, C, Wichmann, HE, Albrecht, E, Gieger, C, Hicks, AA, Johansson, A, Pramstaller, PP, Kathiresan, S, Speliotes, EK, Penninx, B, Hartikainen, AL, Jarvelin, MR, Gyllensten, U, Boomsma, DI, Campbell, H, Wilson, JF, Chanock, SJ, Farrall, M, Goel, A, Medina-Gomez, C, Rivadeneira, F, Estrada Gil, K, Uitterlinden, A , Hofman, B , Zillikens, MC, Heijer, M, Kiemeney, LA, del Maschio, A, Hall, P, Tyrer, J, Teumer, A, Volzke, H, Kovacs, P, Tonjes, A, Mangino, M, Spector, TD, Hayward, C, Rudan, I, Hall, AS, Samani, NJ, Attwood, AP, Sambrook, JG, Hung, J, Palmer, LJ, Lokki, ML, Sinisalo, J, Boucher, G, Huikuri, H, Lorentzon, M, Ohlsson, C, Eklund, N, Eriksson, JG, Barlassina, C, Rivolta, C, Nolte, IM, Snieder, H, van der Klauw, MM, van Vliet-Ostaptchouk, JV, Gejman, PV, Shi, JX, Jacobs, KB, Wang, ZM, Bakker, SJL, Leach, IM, Navis, G, van der Harst, P, Martin, NG, Medland, SE, Montgomery, GW, Yang, J, Chasman, DI, Ridker, PM, Rose, LM, Lehtimaki, T, Raitakari, O, Absher, D, Iribarren, C, Basart, H, Hovingh, KG, Hypponen, E, Power, C, Anderson, D, Beilby, JP, Hui, JN, Jolley, J, Sager, H, Bornstein, SR, Schwarz, PEH, Kristiansson, K, Perola, M, Lindstrom, J, Swift, AJ, Uusitupa, M, Atalay, M, Lakka, TA, Rauramaa, R, Bolton, JL, Fowkes, G, Fraser, RM, Price, JF, Fischer, K, KrjutAikov, K, Metspalu, A, Mihailov, E, Langenberg, C, Luan, JA, Ong, KK, Chines, PS, Keinanen-Kiukaanniemi, SM, Saaristo, TE, Edkins, S, Franks, PW, Hallmans, G, Shungin, D, Morris, AD, Palmer, CNA, Erbel, R, Moebus, S, Nothen, MM, Pechlivanis, S, Hveem, K, Narisu, N, Hamsten, A, Humphries, SE, Strawbridge, RJ, Tremoli, E, Grallert, H, Thorand, B, Illig, T, Koenig, W, Muller-Nurasyid, M, Peters, A, Boehm, BO, Kleber, ME, Marz, W, Winkelmann, BR, Kuusisto, J, Laakso, M, Arveiler, D, Cesana, G, Kuulasmaa, K, Virtamo, J, Yarnell, JWG, Kuh, D, Wong, A, Lind, L, de Faire, U, Gigante, B, Magnusson, PKE, Pedersen, NL, Dedoussis, G, Dimitriou, M, Kolovou, G, Kanoni, S, Stirrups, K, Bonnycastle, LL, Njolstad, I, Wilsgaard, T, Ganna, A, Rehnberg, E, Hingorani, A, Kivimaki, M, Kumari, M, Assimes, TL, Barroso, IS, Boehnke, M, Borecki, IB, Deloukas, P, Fox, CS, Frayling, T, Groop, LC, Haritunians, T, Hunter, D, Ingelsson, E, Kaplan, R, Mohlke, KL, O'Connell, JR, Schlessinger, D, Strachan, DP, Stefansson, K, Duijn, C, Abecasis, GR, McCarthy, MI, Hirschhorn, JN, Qi, L, Loos, RJF, Lindgren, CM, North, KE & Heid, IM 2013, 'Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits', PLoS Genetics (print), vol. 9, no. 6. https://doi.org/10.1371/journal.pgen.1003500

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. / Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpelainen, TO; Esko, T; Magi, R; Li, SX; Workalemahu, T; Feitosa, MF; Croteau-Chonka, DC; Day, FR; Fall, T; Ferreira, T; Gustafsson, S; Locke, AE; Mathieson, I; Scherag, A; Vedantam, S; Wood, AR; Liang, LM; Steinthorsdottir, V; Thorleifsson, G; Dermitzakis, ET; Dimas, AS; Karpe, F; Min, JL; Nicholson, G; Clegg, DJ; Person, T; Krohn, JP; Bauer, S; Buechler, C; Eisinger, K; Bonnefond, A; Froguel, P; Hottenga, JJ (Jouke Jan); Prokopenko, I; Waite, LL; Harris, TB; Smith, AV; Shuldiner, AR; McArdle, WL; Caulfield, MJ; Munroe, PB; Gronberg, H; Chen, YDI; Li, G (Guo); Beckmann, JS; Johnson, T; Thorsteinsdottir, U; Teder-Laving, M; Khaw, KT; Wareham, NJ; Zhao, JH; Amin, Najaf; Oostra, Ben; Kraja, AT; Province, MA; Cupples, LA; Heard-Costa, NL; Kaprio, J; Ripatti, S; Surakka, I; Collins, FS; Saramies, J; Tuomilehto, J; Jula, A; Salomaa, V; Erdmann, J; Hengstenberg, C; Loley, C; Schunkert, H; Lamina, C; Wichmann, HE; Albrecht, E; Gieger, C; Hicks, AA; Johansson, A; Pramstaller, PP; Kathiresan, S; Speliotes, EK; Penninx, B; Hartikainen, AL; Jarvelin, MR; Gyllensten, U; Boomsma, DI; Campbell, H; Wilson, JF; Chanock, SJ; Farrall, M; Goel, A; Medina-Gomez, C; Rivadeneira, Fernando; Estrada Gil, Karol; Uitterlinden, André ; Hofman, Bert ; Zillikens, M.C.; Heijer, Mariska; Kiemeney, LA; del Maschio, A; Hall, P; Tyrer, J; Teumer, A; Volzke, H; Kovacs, P; Tonjes, A; Mangino, M; Spector, TD; Hayward, C; Rudan, I; Hall, AS; Samani, NJ; Attwood, AP; Sambrook, JG; Hung, J; Palmer, LJ; Lokki, ML; Sinisalo, J; Boucher, G; Huikuri, H; Lorentzon, M; Ohlsson, C; Eklund, N; Eriksson, JG; Barlassina, C; Rivolta, C; Nolte, IM (Ilja); Snieder, H; van der Klauw, MM (Melanie); van Vliet-Ostaptchouk, JV; Gejman, PV; Shi, JX; Jacobs, KB; Wang, ZM; Bakker, SJL; Leach, IM; Navis, G; van der Harst, P; Martin, NG; Medland, SE; Montgomery, GW; Yang, Jiaqi; Chasman, DI; Ridker, PM; Rose, LM; Lehtimaki, T; Raitakari, O; Absher, D; Iribarren, C; Basart, H; Hovingh, KG; Hypponen, E; Power, C; Anderson, D; Beilby, JP; Hui, JN; Jolley, J; Sager, H; Bornstein, SR; Schwarz, PEH; Kristiansson, K; Perola, M; Lindstrom, J; Swift, AJ; Uusitupa, M; Atalay, M; Lakka, TA; Rauramaa, R; Bolton, JL; Fowkes, G; Fraser, RM; Price, JF; Fischer, K (Kirsten); KrjutAikov, K; Metspalu, A; Mihailov, E; Langenberg, C; Luan, JA; Ong, KK; Chines, PS; Keinanen-Kiukaanniemi, SM; Saaristo, TE; Edkins, S; Franks, PW; Hallmans, G; Shungin, D; Morris, AD; Palmer, CNA; Erbel, R; Moebus, S; Nothen, MM; Pechlivanis, S; Hveem, K; Narisu, N; Hamsten, A; Humphries, SE; Strawbridge, RJ; Tremoli, E; Grallert, H; Thorand, B; Illig, T; Koenig, W; Muller-Nurasyid, M; Peters, A; Boehm, BO; Kleber, ME; Marz, W; Winkelmann, BR; Kuusisto, J; Laakso, M; Arveiler, D; Cesana, G; Kuulasmaa, K; Virtamo, J; Yarnell, JWG; Kuh, D; Wong, A; Lind, L; de Faire, U; Gigante, B; Magnusson, PKE; Pedersen, NL; Dedoussis, G; Dimitriou, M; Kolovou, G; Kanoni, S; Stirrups, K; Bonnycastle, LL; Njolstad, I; Wilsgaard, T; Ganna, A; Rehnberg, E; Hingorani, A; Kivimaki, M; Kumari, M; Assimes, TL; Barroso, IS; Boehnke, M; Borecki, IB; Deloukas, P; Fox, CS; Frayling, T; Groop, LC; Haritunians, T; Hunter, D; Ingelsson, E; Kaplan, R; Mohlke, KL; O'Connell, JR; Schlessinger, D; Strachan, DP; Stefansson, K; Duijn, Cornelia; Abecasis, GR; McCarthy, MI; Hirschhorn, JN; Qi, L; Loos, RJF; Lindgren, CM; North, KE; Heid, IM.

In: PLoS Genetics (print), Vol. 9, No. 6, 2013.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

AU - Randall, JC

AU - Winkler, TW

AU - Kutalik, Z

AU - Berndt, SI

AU - Jackson, AU

AU - Monda, KL

AU - Kilpelainen, TO

AU - Esko, T

AU - Magi, R

AU - Li, SX

AU - Workalemahu, T

AU - Feitosa, MF

AU - Croteau-Chonka, DC

AU - Day, FR

AU - Fall, T

AU - Ferreira, T

AU - Gustafsson, S

AU - Locke, AE

AU - Mathieson, I

AU - Scherag, A

AU - Vedantam, S

AU - Wood, AR

AU - Liang, LM

AU - Steinthorsdottir, V

AU - Thorleifsson, G

AU - Dermitzakis, ET

AU - Dimas, AS

AU - Karpe, F

AU - Min, JL

AU - Nicholson, G

AU - Clegg, DJ

AU - Person, T

AU - Krohn, JP

AU - Bauer, S

AU - Buechler, C

AU - Eisinger, K

AU - Bonnefond, A

AU - Froguel, P

AU - Hottenga, JJ (Jouke Jan)

AU - Prokopenko, I

AU - Waite, LL

AU - Harris, TB

AU - Smith, AV

AU - Shuldiner, AR

AU - McArdle, WL

AU - Caulfield, MJ

AU - Munroe, PB

AU - Gronberg, H

AU - Chen, YDI

AU - Li, G (Guo)

AU - Beckmann, JS

AU - Johnson, T

AU - Thorsteinsdottir, U

AU - Teder-Laving, M

AU - Khaw, KT

AU - Wareham, NJ

AU - Zhao, JH

AU - Amin, Najaf

AU - Oostra, Ben

AU - Kraja, AT

AU - Province, MA

AU - Cupples, LA

AU - Heard-Costa, NL

AU - Kaprio, J

AU - Ripatti, S

AU - Surakka, I

AU - Collins, FS

AU - Saramies, J

AU - Tuomilehto, J

AU - Jula, A

AU - Salomaa, V

AU - Erdmann, J

AU - Hengstenberg, C

AU - Loley, C

AU - Schunkert, H

AU - Lamina, C

AU - Wichmann, HE

AU - Albrecht, E

AU - Gieger, C

AU - Hicks, AA

AU - Johansson, A

AU - Pramstaller, PP

AU - Kathiresan, S

AU - Speliotes, EK

AU - Penninx, B

AU - Hartikainen, AL

AU - Jarvelin, MR

AU - Gyllensten, U

AU - Boomsma, DI

AU - Campbell, H

AU - Wilson, JF

AU - Chanock, SJ

AU - Farrall, M

AU - Goel, A

AU - Medina-Gomez, C

AU - Rivadeneira, Fernando

AU - Estrada Gil, Karol

AU - Uitterlinden, André

AU - Hofman, Bert

AU - Zillikens, M.C.

AU - Heijer, Mariska

AU - Kiemeney, LA

AU - del Maschio, A

AU - Hall, P

AU - Tyrer, J

AU - Teumer, A

AU - Volzke, H

AU - Kovacs, P

AU - Tonjes, A

AU - Mangino, M

AU - Spector, TD

AU - Hayward, C

AU - Rudan, I

AU - Hall, AS

AU - Samani, NJ

AU - Attwood, AP

AU - Sambrook, JG

AU - Hung, J

AU - Palmer, LJ

AU - Lokki, ML

AU - Sinisalo, J

AU - Boucher, G

AU - Huikuri, H

AU - Lorentzon, M

AU - Ohlsson, C

AU - Eklund, N

AU - Eriksson, JG

AU - Barlassina, C

AU - Rivolta, C

AU - Nolte, IM (Ilja)

AU - Snieder, H

AU - van der Klauw, MM (Melanie)

AU - van Vliet-Ostaptchouk, JV

AU - Gejman, PV

AU - Shi, JX

AU - Jacobs, KB

AU - Wang, ZM

AU - Bakker, SJL

AU - Leach, IM

AU - Navis, G

AU - van der Harst, P

AU - Martin, NG

AU - Medland, SE

AU - Montgomery, GW

AU - Yang, Jiaqi

AU - Chasman, DI

AU - Ridker, PM

AU - Rose, LM

AU - Lehtimaki, T

AU - Raitakari, O

AU - Absher, D

AU - Iribarren, C

AU - Basart, H

AU - Hovingh, KG

AU - Hypponen, E

AU - Power, C

AU - Anderson, D

AU - Beilby, JP

AU - Hui, JN

AU - Jolley, J

AU - Sager, H

AU - Bornstein, SR

AU - Schwarz, PEH

AU - Kristiansson, K

AU - Perola, M

AU - Lindstrom, J

AU - Swift, AJ

AU - Uusitupa, M

AU - Atalay, M

AU - Lakka, TA

AU - Rauramaa, R

AU - Bolton, JL

AU - Fowkes, G

AU - Fraser, RM

AU - Price, JF

AU - Fischer, K (Kirsten)

AU - KrjutAikov, K

AU - Metspalu, A

AU - Mihailov, E

AU - Langenberg, C

AU - Luan, JA

AU - Ong, KK

AU - Chines, PS

AU - Keinanen-Kiukaanniemi, SM

AU - Saaristo, TE

AU - Edkins, S

AU - Franks, PW

AU - Hallmans, G

AU - Shungin, D

AU - Morris, AD

AU - Palmer, CNA

AU - Erbel, R

AU - Moebus, S

AU - Nothen, MM

AU - Pechlivanis, S

AU - Hveem, K

AU - Narisu, N

AU - Hamsten, A

AU - Humphries, SE

AU - Strawbridge, RJ

AU - Tremoli, E

AU - Grallert, H

AU - Thorand, B

AU - Illig, T

AU - Koenig, W

AU - Muller-Nurasyid, M

AU - Peters, A

AU - Boehm, BO

AU - Kleber, ME

AU - Marz, W

AU - Winkelmann, BR

AU - Kuusisto, J

AU - Laakso, M

AU - Arveiler, D

AU - Cesana, G

AU - Kuulasmaa, K

AU - Virtamo, J

AU - Yarnell, JWG

AU - Kuh, D

AU - Wong, A

AU - Lind, L

AU - de Faire, U

AU - Gigante, B

AU - Magnusson, PKE

AU - Pedersen, NL

AU - Dedoussis, G

AU - Dimitriou, M

AU - Kolovou, G

AU - Kanoni, S

AU - Stirrups, K

AU - Bonnycastle, LL

AU - Njolstad, I

AU - Wilsgaard, T

AU - Ganna, A

AU - Rehnberg, E

AU - Hingorani, A

AU - Kivimaki, M

AU - Kumari, M

AU - Assimes, TL

AU - Barroso, IS

AU - Boehnke, M

AU - Borecki, IB

AU - Deloukas, P

AU - Fox, CS

AU - Frayling, T

AU - Groop, LC

AU - Haritunians, T

AU - Hunter, D

AU - Ingelsson, E

AU - Kaplan, R

AU - Mohlke, KL

AU - O'Connell, JR

AU - Schlessinger, D

AU - Strachan, DP

AU - Stefansson, K

AU - Duijn, Cornelia

AU - Abecasis, GR

AU - McCarthy, MI

AU - Hirschhorn, JN

AU - Qi, L

AU - Loos, RJF

AU - Lindgren, CM

AU - North, KE

AU - Heid, IM

PY - 2013

Y1 - 2013

U2 - 10.1371/journal.pgen.1003500

DO - 10.1371/journal.pgen.1003500

M3 - Article

VL - 9

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 6

ER -