Short term micro-evolution and PCR-detection of methicillin-resistant and -susceptible Staphylococcus aureus sequence type 398

Willem van Wamel, S Manaskova, AC Fluit, Henri Verbrugh, AJ de Neeling, E van Duijkeren, Alex Belkum

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Micro-evolutionary analysis of 70 ST398 isolates by pulsed-field gel electrophoresis (PFGE) using Cfr9I revealed three sub-clones with abundant inter- and intra-sub-clone heterogeneity in spa- and SCCmec-types. In addition, we developed two specific PCRs for the detection of Staphylococcus aureus sequence type 398 (ST 398) isolates with 100% specificity and high sensitivity.
Original languageUndefined/Unknown
Pages (from-to)119-122
Number of pages4
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Issue number1
Publication statusPublished - 2010

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