Signal targeting with alternating radiofrequency (STAR) sequences: Application to MR angiography

Robert R. Edelman*, Bettina Siewert, Mary Adamis, Jochen Gaa, Gerhard Laub, Piotr Wielopolski

*Corresponding author for this work

Research output: Contribution to journalArticleProfessionalpeer-review

153 Citations (Scopus)


We describe a time of flight subtraction method for cine MR angiography that provides nearly perfect suppression of background signal intensity with excellent flow contrast. The method consists of a preparation phase, during which the longitudinal magnetization of the target tissue is inverted on alternate acquisitions and the background tissue is presaturated, followed by a readout phase using a cine segmented turboFLASH sequence with a shared echo modification to improve temporal resolution. With appropriate alternation of the phases of the radiofrequency excitation pulses, there is cancellation of the background signal intensity but flow signal is optimized. By using a thick section (up to 25 mm), substantial portions of the vascular territory are encompassed in a single plane. This permits rapid, dynamic assessment of flow patterns in areas such as the circle of Willis, carotid bifurcation, or renal arteries. Applications of the method for bright and dark blood cine MR angiography are demonstrated.

Original languageEnglish
Pages (from-to)233-238
Number of pages6
JournalMagnetic Resonance in Medicine
Issue number2
Publication statusPublished - Feb 1994
Externally publishedYes


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