Abstract
Every year approximately one thousand people in the Netherlands are diagnosed
with diffuse glioma, a type of infiltrative brain tumor that originates from the
glial cells. There is no curative treatment available for adults diagnosed with
a diffuse glioma, although surgical resection, radiotherapy and chemotherapy
are used to improve prognosis and decrease symptoms. Low-grade glioma can
remain stable for long periods of time before, inevitably, malignant progression
occurs. The radiological assessment of glioma through magnetic resonance
imaging (MRI) plays an important role in the management of glioma. In
this thesis I explore the role of quantitative measurements, emerging imaging
markers and predictive modelling in the management of glioma. These methods
can aid the radiologist to predict the timing, location and severity of tumor
progression, to ultimately improve the quality of life for glioma patients.
with diffuse glioma, a type of infiltrative brain tumor that originates from the
glial cells. There is no curative treatment available for adults diagnosed with
a diffuse glioma, although surgical resection, radiotherapy and chemotherapy
are used to improve prognosis and decrease symptoms. Low-grade glioma can
remain stable for long periods of time before, inevitably, malignant progression
occurs. The radiological assessment of glioma through magnetic resonance
imaging (MRI) plays an important role in the management of glioma. In
this thesis I explore the role of quantitative measurements, emerging imaging
markers and predictive modelling in the management of glioma. These methods
can aid the radiologist to predict the timing, location and severity of tumor
progression, to ultimately improve the quality of life for glioma patients.
Original language | English |
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Awarding Institution |
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Supervisors/Advisors |
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Award date | 13 Mar 2024 |
Place of Publication | Rotterdam |
Print ISBNs | 978-94-6483-765-0 |
Publication status | Published - 13 Mar 2024 |