Skull and dural metastases

Ben P.W. Janssen; Peter Sillevis Smitt

doi:10.1007/978-1-59259-317-0_8

Skull and dural metastases

Ben P.W. Janssen, Peter Sillevis Smitt

Neurology

Research output: Chapter/Conference proceeding › Chapter › Academic

Abstract

Skull and durai metastases are caused by hematogenous spread of malignant cells from distant tumors. Over several decades their frequency has appeared to rise, probably as a consequence of better neuroimaging tools and prolonged patient survival. Skull or durai metastases can either be symptomatic or go unrecognized, and in some instances are found accidentally. Nevertheless, if untreated, progressive neurologic deficit and discomfort may follow. Early detection and appropriate treatment can improve or maintain quality of life, since antitumor therapy is effective in a majority of patients. In this chapter we will discuss epidemiology, pathophysiology, clinical signs and symptoms, diagnosis and treatment of skull and durai metastases.

Original language	English
Title of host publication	Cancer neurology in clinical practice
Editors	D. Schiff, P.Y. Wen
Place of Publication	London
Publisher	Humana Press
Chapter	8
Pages	87-93
Number of pages	7
ISBN (Electronic)	978-1-59259-317-0
ISBN (Print)	0896039226, 978-1-4757-4703-4
DOIs	https://doi.org/10.1007/978-1-59259-317-0_8
Publication status	Published - 2002

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EMC MM-03-44-06

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10.1007/978-1-59259-317-0_8

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abstract = "Skull and durai metastases are caused by hematogenous spread of malignant cells from distant tumors. Over several decades their frequency has appeared to rise, probably as a consequence of better neuroimaging tools and prolonged patient survival. Skull or durai metastases can either be symptomatic or go unrecognized, and in some instances are found accidentally. Nevertheless, if untreated, progressive neurologic deficit and discomfort may follow. Early detection and appropriate treatment can improve or maintain quality of life, since antitumor therapy is effective in a majority of patients. In this chapter we will discuss epidemiology, pathophysiology, clinical signs and symptoms, diagnosis and treatment of skull and durai metastases.",

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AB - Skull and durai metastases are caused by hematogenous spread of malignant cells from distant tumors. Over several decades their frequency has appeared to rise, probably as a consequence of better neuroimaging tools and prolonged patient survival. Skull or durai metastases can either be symptomatic or go unrecognized, and in some instances are found accidentally. Nevertheless, if untreated, progressive neurologic deficit and discomfort may follow. Early detection and appropriate treatment can improve or maintain quality of life, since antitumor therapy is effective in a majority of patients. In this chapter we will discuss epidemiology, pathophysiology, clinical signs and symptoms, diagnosis and treatment of skull and durai metastases.

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SN - 978-1-4757-4703-4

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BT - Cancer neurology in clinical practice

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A2 - Wen, P.Y.

PB - Humana Press

CY - London

ER -

Skull and dural metastases

Abstract

Bibliographical note

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