Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

S. A.L. Bartels; M. S. Vlug; Collaborative LAFA Study Group; M. W. Hollmann; M. G.W. Dijkgraaf; D. T. Ubbink; H. A. Cense; B. A. Van Wagensveld; A. F. Engel; M. F. Gerhards; W. A. Bemelman

doi:10.1002/bjs.9585

Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

S. A.L. Bartels, M. S. Vlug, Collaborative LAFA Study Group, M. W. Hollmann, M. G.W. Dijkgraaf, D. T. Ubbink, H. A. Cense, B. A. Van Wagensveld, A. F. Engel, M. F. Gerhards, W. A. Bemelman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

80 Citations (Scopus)

Abstract

Background:

Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer.

Methods:

The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care.

Results:

Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales).

Conclusion:

Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

Original language	English
Pages (from-to)	1153-1159
Number of pages	7
Journal	British Journal of Surgery
Volume	101
Issue number	9
DOIs	https://doi.org/10.1002/bjs.9585
Publication status	Published - Aug 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/bjs.9585Licence: Unspecified

Cite this

Bartels, S. A. L., Vlug, M. S., Collaborative LAFA Study Group, Hollmann, M. W., Dijkgraaf, M. G. W., Ubbink, D. T., Cense, H. A., Van Wagensveld, B. A., Engel, A. F., Gerhards, M. F., & Bemelman, W. A. (2014). Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study). British Journal of Surgery, 101(9), 1153-1159. https://doi.org/10.1002/bjs.9585

@article{a0b617c6bc934a938726aac3a6b7be5a,

title = "Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)",

abstract = "Background: Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods: The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results: Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion: Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery",

author = "Bartels, {S. A.L.} and Vlug, {M. S.} and {Collaborative LAFA Study Group} and Hollmann, {M. W.} and Dijkgraaf, {M. G.W.} and Ubbink, {D. T.} and Cense, {H. A.} and {Van Wagensveld}, {B. A.} and Engel, {A. F.} and Gerhards, {M. F.} and Bemelman, {W. A.} and Tanis, {P. J.}",

year = "2014",

month = aug,

doi = "10.1002/bjs.9585",

language = "English",

volume = "101",

pages = "1153--1159",

journal = "British Journal of Surgery",

issn = "0007-1323",

publisher = "John Wiley & Sons Ltd.",

number = "9",

}

Bartels, SAL, Vlug, MS, Collaborative LAFA Study Group, Hollmann, MW, Dijkgraaf, MGW, Ubbink, DT, Cense, HA, Van Wagensveld, BA, Engel, AF, Gerhards, MF & Bemelman, WA 2014, 'Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)', British Journal of Surgery, vol. 101, no. 9, pp. 1153-1159. https://doi.org/10.1002/bjs.9585

TY - JOUR

T1 - Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

AU - Bartels, S. A.L.

AU - Vlug, M. S.

AU - Collaborative LAFA Study Group

AU - Hollmann, M. W.

AU - Dijkgraaf, M. G.W.

AU - Ubbink, D. T.

AU - Cense, H. A.

AU - Van Wagensveld, B. A.

AU - Engel, A. F.

AU - Gerhards, M. F.

AU - Bemelman, W. A.

AU - Tanis, P. J.

PY - 2014/8

Y1 - 2014/8

N2 - Background: Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods: The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results: Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion: Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

AB - Background: Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods: The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results: Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion: Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

UR - http://www.scopus.com/inward/record.url?scp=84904578628&partnerID=8YFLogxK

U2 - 10.1002/bjs.9585

DO - 10.1002/bjs.9585

M3 - Article

C2 - 24977342

AN - SCOPUS:84904578628

SN - 0007-1323

VL - 101

SP - 1153

EP - 1159

JO - British Journal of Surgery

JF - British Journal of Surgery

IS - 9

ER -

Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this