Social isolation, social support, loneliness and cardiovascular disease risk factors: A cross-sectional study among older adults

Jessie Hu, Sharyn M. Fitzgerald, Alice J. Owen, Joanne Ryan, Johanna Joyce, Enayet Chowdhury, Christopher M. Reid, Carlene Britt, Robyn L. Woods, John J. McNeil, Rosanne Freak-Poli*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)


Background: Social health reflects one’s ability to form interpersonal relationships. Poor social health is a risk factor for cardiovascular disease (CVD), however an in-depth exploration of the link through CVD risk factors is lacking. Aim: To examine the relationship between social health (social isolation, social support, loneliness) and CVD risk factors among healthy older women and men. Methods: Data were from 11,498 healthy community-dwelling Australians aged ≥70 years from the ASPirin in Reducing Events in the Elderly (ASPREE) trial and the ASPREE Longitudinal Study of Older Persons sub-study. Ten-year CVD risk was estimated using the Atherosclerotic CVD Risk Scale (ASCVDRS) and the Framingham Risk Score (FRS). Results: Physical inactivity and experiencing depressive symptoms were the only CVD risk factors that consistently differed by all three social health constructs. Loneliness was associated with greater ASCVDRS (women: β = 0.01, p < 0.05; men: β = 0.03, p < 0.001), social isolation with greater FRS (women: β = 0.02, p < 0.01; men: β = 0.03, p < 0.01) and the social health composite of being lonely (regardless of social isolation and/or social support status) with greater ASCVDRS (women: β = 0.01, p = 0.02; men: β = 0.03, p < 0.001). Among men, loneliness was also associated with greater FRS (β = 0.03, p < 0.001) and social support with greater ASCVDRS (β = 0.02, p = 0.01). Men were more socially isolated, less socially supported and less lonely than women. Conclusion: Social isolation, social support and loneliness displayed diverse relationships with CVD risk factors and risk scores, emphasising the importance of distinguishing between these constructs. These findings inform on potential avenues to manage poor social health and CVD risk among older adults.

Original languageEnglish
Pages (from-to)1795-1809
Number of pages15
JournalInternational Journal of Geriatric Psychiatry
Issue number11
Early online date7 Jul 2021
Publication statusPublished - Nov 2021


Dive into the research topics of 'Social isolation, social support, loneliness and cardiovascular disease risk factors: A cross-sectional study among older adults'. Together they form a unique fingerprint.

Cite this