Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors

M van Vliet, M (Mike) Kliffen, Gabriel Krestin, CF (Cornelis) van Dijke

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Soft tissue sarcomas comprise approximately 1% of malignant tumors. There are more than 50 subtypes, but pleomorphic sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, and malignant peripheral nerve sheath tumor account for 75%. Differentiation between these subtypes is difficult because they often present with a painless enlarging mass, and share many histological and MR imaging features. Nonetheless, subdifferentiation is important because the different subtypes have different prognoses and therapeutic strategies. In this manuscript we discuss the clinical, histological, and MR imaging features of soft tissue sarcomas according to the WHO classification. An overview is provided and differentiating features are discussed that can help to narrow down the differential diagnosis.
Original languageUndefined/Unknown
Pages (from-to)1499-1511
Number of pages13
JournalEuropean Radiology
Issue number6
Publication statusPublished - 2009

Research programs

  • EMC NIHES-03-30-03

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