TY - JOUR
T1 - Spontaneous sternal fracture due to multiple myeloma requiring extensive surgical repair
AU - Reuling, Ellen M.B.P.
AU - Jakma, Tijs S.C.
AU - Schnater, Johannes Marco
AU - Westerweel, Peter E.
PY - 2015/11/30
Y1 - 2015/11/30
N2 - Spontaneous sternal fracture is a well-known complication of multiple myeloma due to osteolytic bone lesions. The possibility of a multiple myeloma should be thoroughly investigated in patients presenting with a spontaneous sternal fracture. This work up should go beyond protein electrophoresis alone as a monoclonal paraprotein is not always present. In some cases, the myeloma plasma cell clone produces only the free light chain (κ or λ) or may even be non-secretory. The underlying plasma cell dyscrasia is treated with chemotherapy and, if needed, local radiotherapy. However, for patients with a fracture causing persistent pain and physical discomfort, internal fixation may be additionally required. We present a case of a patient who presented with a displaced pathological sternal fracture. She was treated with chemotherapy, radiotherapy and an open reduction and internal fixation with a Locking Compression Plate (LCP). This technique offers a feasible option for rigid fixation of pathological fractures.
AB - Spontaneous sternal fracture is a well-known complication of multiple myeloma due to osteolytic bone lesions. The possibility of a multiple myeloma should be thoroughly investigated in patients presenting with a spontaneous sternal fracture. This work up should go beyond protein electrophoresis alone as a monoclonal paraprotein is not always present. In some cases, the myeloma plasma cell clone produces only the free light chain (κ or λ) or may even be non-secretory. The underlying plasma cell dyscrasia is treated with chemotherapy and, if needed, local radiotherapy. However, for patients with a fracture causing persistent pain and physical discomfort, internal fixation may be additionally required. We present a case of a patient who presented with a displaced pathological sternal fracture. She was treated with chemotherapy, radiotherapy and an open reduction and internal fixation with a Locking Compression Plate (LCP). This technique offers a feasible option for rigid fixation of pathological fractures.
UR - http://www.scopus.com/inward/record.url?scp=84954545681&partnerID=8YFLogxK
U2 - 10.1136/bcr-2015-211498
DO - 10.1136/bcr-2015-211498
M3 - Article
C2 - 26621901
AN - SCOPUS:84954545681
SN - 1757-790X
VL - 2015
JO - BMJ Case Reports
JF - BMJ Case Reports
M1 - 211498
ER -