Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2

E Gane; D Kershenobich; C Seguin-Devaux; P Kristian; I Aho; O Dalgard; I Shestakova; P Nymadawa; S Blach; S Acharya; AC Anand; MI Andersson; V Arendt; P Arkkila; O Baatarkhuu; K Barclay; Z Ben-Ari; C Bergin; F Bessone; N Blokhina; CR Brunton; G Choudhuri; V Chulanov; L Cisneros; EA Croes; YA Dahgwahdorj; JR Daruich; NR Dashdorj; D Davaadorj; Rob de Knegt; M de Vree; AC Gadano; E Gower; W Halota; A Hatzakis; C Henderson; P Hoffmann; J Hornell; D Houlihan; S Hrusovsky; P Jarcuska; K Kostrzewska; M Leshno; Y Lurie; A Mahomed; N Mamonova; N Mendez-Sanchez; J Mossong; S Norris; E Nurmukhametova; M Oltman; J Oyunbileg; T Oyunsuren; G Papatheodoridis; N Pimenov; M Prins; P Puri; S Radke; A Rakhmanova; H Razavi; K Razavi-Shearer; HW Reesink; E Ridruejo; R Safadi; O Sagalova; JF Sanchez Avila; R Sanduijav; V Saraswat; I Schreter; SR Shah; A Shevaldin; O Shibolet; MO Silva; S Sokolov; M Sonderup; K Souliotis; CW Spearman; T Staub; C Stedman; EA Strebkova; D Struck; V Sypsa; K Tomasiewicz; L Undram; Adriaan van der Meer; D van Santen; I Veldhuijzen; FG Villamil; S Willemse; E Zuckerman; FR Zuure; N Prabdial-Sing; R Flisiak; C Estes

doi:10.1111/jvh.12352

Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2

E Gane, D Kershenobich, C Seguin-Devaux, P Kristian, I Aho, O Dalgard, I Shestakova, P Nymadawa, S Blach, S Acharya, AC Anand, MI Andersson, V Arendt, P Arkkila, O Baatarkhuu, K Barclay, Z Ben-Ari, C Bergin, F Bessone, N BlokhinaCR Brunton, G Choudhuri, V Chulanov, L Cisneros, EA Croes, YA Dahgwahdorj, JR Daruich, NR Dashdorj, D Davaadorj, Rob de Knegt, M de Vree, AC Gadano, E Gower, W Halota, A Hatzakis, C Henderson, P Hoffmann, J Hornell, D Houlihan, S Hrusovsky, P Jarcuska, K Kostrzewska, M Leshno, Y Lurie, A Mahomed, N Mamonova, N Mendez-Sanchez, J Mossong, S Norris, E Nurmukhametova, M Oltman, J Oyunbileg, T Oyunsuren, G Papatheodoridis, N Pimenov, M Prins, P Puri, S Radke, A Rakhmanova, H Razavi, K Razavi-Shearer, HW Reesink, E Ridruejo, R Safadi, O Sagalova, JF Sanchez Avila, R Sanduijav, V Saraswat, I Schreter, SR Shah, A Shevaldin, O Shibolet, MO Silva, S Sokolov, M Sonderup, K Souliotis, CW Spearman, T Staub, C Stedman, EA Strebkova, D Struck, V Sypsa, K Tomasiewicz, L Undram, Adriaan van der Meer, D van Santen, I Veldhuijzen, FG Villamil, S Willemse, E Zuckerman, FR Zuure, N Prabdial-Sing, R Flisiak, C Estes

Gastroenterology & Hepatology

Research output: Contribution to journal › Article › Academic › peer-review

55 Citations (Scopus)

Abstract

The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.

Original language	Undefined/Unknown
Pages (from-to)	46-73
Number of pages	28
Journal	Journal of Viral Hepatitis
Volume	22
DOIs	https://doi.org/10.1111/jvh.12352
Publication status	Published - 2015

Research programs

EMC MM-04-20-01

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/jvh.12352

http://hdl.handle.net/1765/83589

Cite this

Gane, E., Kershenobich, D., Seguin-Devaux, C., Kristian, P., Aho, I., Dalgard, O., Shestakova, I., Nymadawa, P., Blach, S., Acharya, S., Anand, AC., Andersson, MI., Arendt, V., Arkkila, P., Baatarkhuu, O., Barclay, K., Ben-Ari, Z., Bergin, C., Bessone, F., ... Estes, C. (2015). Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2. Journal of Viral Hepatitis, 22, 46-73. https://doi.org/10.1111/jvh.12352

@article{d704261fea944ab0b1f0d3ed98406f41,

title = "Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2",

abstract = "The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.",

author = "E Gane and D Kershenobich and C Seguin-Devaux and P Kristian and I Aho and O Dalgard and I Shestakova and P Nymadawa and S Blach and S Acharya and AC Anand and MI Andersson and V Arendt and P Arkkila and O Baatarkhuu and K Barclay and Z Ben-Ari and C Bergin and F Bessone and N Blokhina and CR Brunton and G Choudhuri and V Chulanov and L Cisneros and EA Croes and YA Dahgwahdorj and JR Daruich and NR Dashdorj and D Davaadorj and {de Knegt}, Rob and {de Vree}, M and AC Gadano and E Gower and W Halota and A Hatzakis and C Henderson and P Hoffmann and J Hornell and D Houlihan and S Hrusovsky and P Jarcuska and K Kostrzewska and M Leshno and Y Lurie and A Mahomed and N Mamonova and N Mendez-Sanchez and J Mossong and S Norris and E Nurmukhametova and M Oltman and J Oyunbileg and T Oyunsuren and G Papatheodoridis and N Pimenov and M Prins and P Puri and S Radke and A Rakhmanova and H Razavi and K Razavi-Shearer and HW Reesink and E Ridruejo and R Safadi and O Sagalova and {Sanchez Avila}, JF and R Sanduijav and V Saraswat and I Schreter and SR Shah and A Shevaldin and O Shibolet and MO Silva and S Sokolov and M Sonderup and K Souliotis and CW Spearman and T Staub and C Stedman and EA Strebkova and D Struck and V Sypsa and K Tomasiewicz and L Undram and {van der Meer}, Adriaan and {van Santen}, D and I Veldhuijzen and FG Villamil and S Willemse and E Zuckerman and FR Zuure and N Prabdial-Sing and R Flisiak and C Estes",

year = "2015",

doi = "10.1111/jvh.12352",

language = "Undefined/Unknown",

volume = "22",

pages = "46--73",

journal = "Journal of Viral Hepatitis",

issn = "1352-0504",

publisher = "Wiley-Blackwell Publishing Ltd",

}

Gane, E, Kershenobich, D, Seguin-Devaux, C, Kristian, P, Aho, I, Dalgard, O, Shestakova, I, Nymadawa, P, Blach, S, Acharya, S, Anand, AC, Andersson, MI, Arendt, V, Arkkila, P, Baatarkhuu, O, Barclay, K, Ben-Ari, Z, Bergin, C, Bessone, F, Blokhina, N, Brunton, CR, Choudhuri, G, Chulanov, V, Cisneros, L, Croes, EA, Dahgwahdorj, YA, Daruich, JR, Dashdorj, NR, Davaadorj, D, de Knegt, R, de Vree, M, Gadano, AC, Gower, E, Halota, W, Hatzakis, A, Henderson, C, Hoffmann, P, Hornell, J, Houlihan, D, Hrusovsky, S, Jarcuska, P, Kostrzewska, K, Leshno, M, Lurie, Y, Mahomed, A, Mamonova, N, Mendez-Sanchez, N, Mossong, J, Norris, S, Nurmukhametova, E, Oltman, M, Oyunbileg, J, Oyunsuren, T, Papatheodoridis, G, Pimenov, N, Prins, M, Puri, P, Radke, S, Rakhmanova, A, Razavi, H, Razavi-Shearer, K, Reesink, HW, Ridruejo, E, Safadi, R, Sagalova, O, Sanchez Avila, JF, Sanduijav, R, Saraswat, V, Schreter, I, Shah, SR, Shevaldin, A, Shibolet, O, Silva, MO, Sokolov, S, Sonderup, M, Souliotis, K, Spearman, CW, Staub, T, Stedman, C, Strebkova, EA, Struck, D, Sypsa, V, Tomasiewicz, K, Undram, L, van der Meer, A, van Santen, D, Veldhuijzen, I, Villamil, FG, Willemse, S, Zuckerman, E, Zuure, FR, Prabdial-Sing, N, Flisiak, R & Estes, C 2015, 'Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2', Journal of Viral Hepatitis, vol. 22, pp. 46-73. https://doi.org/10.1111/jvh.12352

TY - JOUR

T1 - Strategies to manage hepatitis C virus (HCV) infection disease burden - volume 2

AU - Gane, E

AU - Kershenobich, D

AU - Seguin-Devaux, C

AU - Kristian, P

AU - Aho, I

AU - Dalgard, O

AU - Shestakova, I

AU - Nymadawa, P

AU - Blach, S

AU - Acharya, S

AU - Anand, AC

AU - Andersson, MI

AU - Arendt, V

AU - Arkkila, P

AU - Baatarkhuu, O

AU - Barclay, K

AU - Ben-Ari, Z

AU - Bergin, C

AU - Bessone, F

AU - Blokhina, N

AU - Brunton, CR

AU - Choudhuri, G

AU - Chulanov, V

AU - Cisneros, L

AU - Croes, EA

AU - Dahgwahdorj, YA

AU - Daruich, JR

AU - Dashdorj, NR

AU - Davaadorj, D

AU - de Knegt, Rob

AU - de Vree, M

AU - Gadano, AC

AU - Gower, E

AU - Halota, W

AU - Hatzakis, A

AU - Henderson, C

AU - Hoffmann, P

AU - Hornell, J

AU - Houlihan, D

AU - Hrusovsky, S

AU - Jarcuska, P

AU - Kostrzewska, K

AU - Leshno, M

AU - Lurie, Y

AU - Mahomed, A

AU - Mamonova, N

AU - Mendez-Sanchez, N

AU - Mossong, J

AU - Norris, S

AU - Nurmukhametova, E

AU - Oltman, M

AU - Oyunbileg, J

AU - Oyunsuren, T

AU - Papatheodoridis, G

AU - Pimenov, N

AU - Prins, M

AU - Puri, P

AU - Radke, S

AU - Rakhmanova, A

AU - Razavi, H

AU - Razavi-Shearer, K

AU - Reesink, HW

AU - Ridruejo, E

AU - Safadi, R

AU - Sagalova, O

AU - Sanchez Avila, JF

AU - Sanduijav, R

AU - Saraswat, V

AU - Schreter, I

AU - Shah, SR

AU - Shevaldin, A

AU - Shibolet, O

AU - Silva, MO

AU - Sokolov, S

AU - Sonderup, M

AU - Souliotis, K

AU - Spearman, CW

AU - Staub, T

AU - Stedman, C

AU - Strebkova, EA

AU - Struck, D

AU - Sypsa, V

AU - Tomasiewicz, K

AU - Undram, L

AU - van der Meer, Adriaan

AU - van Santen, D

AU - Veldhuijzen, I

AU - Villamil, FG

AU - Willemse, S

AU - Zuckerman, E

AU - Zuure, FR

AU - Prabdial-Sing, N

AU - Flisiak, R

AU - Estes, C

PY - 2015

Y1 - 2015

N2 - The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.

AB - The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios was considered: (i) increased treatment efficacy while holding the treated population constant and (ii) increased treatment efficacy and increased annual treated population. Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. In most countries, the annual treated population had to increase several fold to achieve the largest reductions in HCV-related morbidity and mortality. This suggests that increased capacity for screening and treatment will be critical in many countries. Birth cohort screening is a helpful tool for maximizing resources. In most of the studied countries, the majority of patients were born between 1945 and 1985.

U2 - 10.1111/jvh.12352

DO - 10.1111/jvh.12352

M3 - Article

C2 - 25560841

SN - 1352-0504

VL - 22

SP - 46

EP - 73

JO - Journal of Viral Hepatitis

JF - Journal of Viral Hepatitis

ER -