Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Cecile Janssens, JPA Ioannidis, Cornelia Duijn, J Little, MJ Khoury

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The rapid and continuing progress in gene discovery for complex diseases is fueling interest in the potential application of genetic risk models for clinical and public health practice. The number of studies assessing the predictive ability is steadily increasing, but the quality and completeness of reporting varies. A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies, building on the principles established by previous reporting guidelines. These recommendations aim to enhance the transparency of study reporting, and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct, or analysis. A detailed Explanation and Elaboration document is published on the EJHG website. European Journal of Human Genetics (2011) 19, 833-836; doi:10.1038/ejhg.2011.25; published online 16 March 2011
Original languageUndefined/Unknown
Pages (from-to)833-836
Number of pages4
JournalEuropean Journal of Human Genetics
Issue number8
Publication statusPublished - 2011

Research programs

  • EMC NIHES-01-64-02
  • EMC NIHES-01-64-03

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