Study of skeletal muscle behavior by PET/MRI

David Garcia Juan; Sara Trombella; Benedicte M.A. Delattre; Yann Seimbille; Osman Ratib

doi:10.1109/BHI.2014.6864304

Study of skeletal muscle behavior by PET/MRI

David Garcia Juan, Sara Trombella, Benedicte M.A. Delattre, Yann Seimbille, Osman Ratib

Research output: Contribution to journal › Conference article › Academic › peer-review

2 Citations (Scopus)

Abstract

Increasingly aging population is leading to higher prevalence of musculoskeletal disorders and related muscular dysfunctions, requiring new types of functional investigations in daily clinical practice. Emerging non-invasive imaging techniques, such as hybrid PET/MRI, allow to visualize and to analyze the human body from the anatomical and metabolic point of view in a single scanning session. We aim to investigate both muscle anatomical behaviour by MRI and exercise-related changes in muscle functionality by PET/MRI and [ ¹¹C]Acetate, in view to develop a model of normal resting and exercised muscle. The static and dynamic PET and MRI acquisition protocols that we developed are described. Dedicated processing techniques are defined for the generation and visualization of 4D datasets, including both anatomical and metabolic acquired data. This paper reports the technical framework and methodological approach developed as a first step in our research. Experimental data are being collected and will be included in future validation studies.

Original language	English
Pages (from-to)	61-64
Number of pages	4
Journal	2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014
DOIs	https://doi.org/10.1109/BHI.2014.6864304
Publication status	Published - 2014
Externally published	Yes
Event	2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014 - Valencia, Spain Duration: 1 Jun 2014 → 4 Jun 2014

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title = "Study of skeletal muscle behavior by PET/MRI",

abstract = "Increasingly aging population is leading to higher prevalence of musculoskeletal disorders and related muscular dysfunctions, requiring new types of functional investigations in daily clinical practice. Emerging non-invasive imaging techniques, such as hybrid PET/MRI, allow to visualize and to analyze the human body from the anatomical and metabolic point of view in a single scanning session. We aim to investigate both muscle anatomical behaviour by MRI and exercise-related changes in muscle functionality by PET/MRI and [ 11C]Acetate, in view to develop a model of normal resting and exercised muscle. The static and dynamic PET and MRI acquisition protocols that we developed are described. Dedicated processing techniques are defined for the generation and visualization of 4D datasets, including both anatomical and metabolic acquired data. This paper reports the technical framework and methodological approach developed as a first step in our research. Experimental data are being collected and will be included in future validation studies.",

author = "Juan, {David Garcia} and Sara Trombella and Delattre, {Benedicte M.A.} and Yann Seimbille and Osman Ratib",

year = "2014",

doi = "10.1109/BHI.2014.6864304",

language = "English",

pages = "61--64",

note = "2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014 ; Conference date: 01-06-2014 Through 04-06-2014",

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AU - Juan, David Garcia

AU - Trombella, Sara

AU - Delattre, Benedicte M.A.

AU - Seimbille, Yann

AU - Ratib, Osman

PY - 2014

Y1 - 2014

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AB - Increasingly aging population is leading to higher prevalence of musculoskeletal disorders and related muscular dysfunctions, requiring new types of functional investigations in daily clinical practice. Emerging non-invasive imaging techniques, such as hybrid PET/MRI, allow to visualize and to analyze the human body from the anatomical and metabolic point of view in a single scanning session. We aim to investigate both muscle anatomical behaviour by MRI and exercise-related changes in muscle functionality by PET/MRI and [ 11C]Acetate, in view to develop a model of normal resting and exercised muscle. The static and dynamic PET and MRI acquisition protocols that we developed are described. Dedicated processing techniques are defined for the generation and visualization of 4D datasets, including both anatomical and metabolic acquired data. This paper reports the technical framework and methodological approach developed as a first step in our research. Experimental data are being collected and will be included in future validation studies.

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DO - 10.1109/BHI.2014.6864304

M3 - Conference article

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SP - 61

EP - 64

JO - 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014

JF - 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014

T2 - 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014

Y2 - 1 June 2014 through 4 June 2014

ER -

Study of skeletal muscle behavior by PET/MRI

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