Systematic Review of Treatment Effectiveness and Outcome Measures for Enthesitis in Psoriatic Arthritis

AM Orbai; J Weitz; EL Siegel; S Siebert; LJ Savage; SZ Aydin; J.J. Luime; O Elkayam; B Neerinckx; S Urbancek; K de Vlam; CT Ritchlin

doi:10.3899/jrheum.140878

Systematic Review of Treatment Effectiveness and Outcome Measures for Enthesitis in Psoriatic Arthritis

AM Orbai, J Weitz, EL Siegel, S Siebert, LJ Savage, SZ Aydin, J.J. Luime, O Elkayam, B Neerinckx, S Urbancek, K de Vlam, CT Ritchlin

Rheumatology

Research output: Contribution to journal › Article › Academic › peer-review

51 Citations (Scopus)

Abstract

Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.

Original language	Undefined/Unknown
Pages (from-to)	2290-2294
Number of pages	5
Journal	Journal of Rheumatology
Volume	41
Issue number	11
DOIs	https://doi.org/10.3899/jrheum.140878
Publication status	Published - 2014

Research programs

EMC MUSC-01-31-01

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10.3899/jrheum.140878

Cite this

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title = "Systematic Review of Treatment Effectiveness and Outcome Measures for Enthesitis in Psoriatic Arthritis",

abstract = "Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.",

author = "AM Orbai and J Weitz and EL Siegel and S Siebert and LJ Savage and SZ Aydin and J.J. Luime and O Elkayam and B Neerinckx and S Urbancek and {de Vlam}, K and CT Ritchlin",

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TY - JOUR

T1 - Systematic Review of Treatment Effectiveness and Outcome Measures for Enthesitis in Psoriatic Arthritis

AU - Orbai, AM

AU - Weitz, J

AU - Siegel, EL

AU - Siebert, S

AU - Savage, LJ

AU - Aydin, SZ

AU - Luime, J.J.

AU - Elkayam, O

AU - Neerinckx, B

AU - Urbancek, S

AU - de Vlam, K

AU - Ritchlin, CT

PY - 2014

Y1 - 2014

N2 - Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.

AB - Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.

U2 - 10.3899/jrheum.140878

DO - 10.3899/jrheum.140878

M3 - Article

C2 - 25362713

SN - 0315-162X

VL - 41

SP - 2290

EP - 2294

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 11

ER -