Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

Marjolein Baar; Renata Brandt; Diana Putavet; Julian Klein; Kasper Derks; BRM Bourgeois; S Stryeck; Yvonne Kamp; Hester Willigenburg; Danny Feijtel; Ingrid van der Pluijm; J. Essers; Gert van Cappellen; Wilfred van Ijcken; Adriaan Houtsmuller; Joris Pothof; Ron de Bruin; T Madl; Jan Hoeijmakers; J Campisi; Peter Keizer

doi:10.1016/j.cell.2017.02.031

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

Marjolein Baar, Renata Brandt, Diana Putavet, Julian Klein, Kasper Derks, BRM Bourgeois, S Stryeck, Yvonne Kamp, Hester Willigenburg, Danny Feijtel, Ingrid van der Pluijm, J. Essers, Gert van Cappellen, Wilfred van Ijcken, Adriaan Houtsmuller, Joris Pothof, Ron de Bruin, T Madl, Jan Hoeijmakers, J CampisiPeter Keizer

Research output: Contribution to journal › Article › Academic › peer-review

1153 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	132-147
Number of pages	16
Journal	Cell
Volume	169
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2017.02.031
Publication status	Published - 2017

Research programs

EMC MGC-01-12-03
EMC MM-03-32-04

Access to Document

10.1016/j.cell.2017.02.031

http://hdl.handle.net/1765/98786

Cite this

Baar, M., Brandt, R., Putavet, D., Klein, J., Derks, K., Bourgeois, BRM., Stryeck, S., Kamp, Y., Willigenburg, H., Feijtel, D., van der Pluijm, I., Essers, J., van Cappellen, G., van Ijcken, W., Houtsmuller, A., Pothof, J., de Bruin, R., Madl, T., Hoeijmakers, J., ... Keizer, P. (2017). Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. https://doi.org/10.1016/j.cell.2017.02.031

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title = "Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging",

author = "Marjolein Baar and Renata Brandt and Diana Putavet and Julian Klein and Kasper Derks and BRM Bourgeois and S Stryeck and Yvonne Kamp and Hester Willigenburg and Danny Feijtel and \{van der Pluijm\}, Ingrid and J. Essers and \{van Cappellen\}, Gert and \{van Ijcken\}, Wilfred and Adriaan Houtsmuller and Joris Pothof and \{de Bruin\}, Ron and T Madl and Jan Hoeijmakers and J Campisi and Peter Keizer",

year = "2017",

doi = "10.1016/j.cell.2017.02.031",

language = "Undefined/Unknown",

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Baar, M, Brandt, R, Putavet, D, Klein, J, Derks, K, Bourgeois, BRM, Stryeck, S, Kamp, Y, Willigenburg, H, Feijtel, D, van der Pluijm, I , Essers, J , van Cappellen, G, van Ijcken, W, Houtsmuller, A , Pothof, J , de Bruin, R, Madl, T, Hoeijmakers, J, Campisi, J & Keizer, P 2017, 'Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging', Cell, vol. 169, no. 1, pp. 132-147. https://doi.org/10.1016/j.cell.2017.02.031

TY - JOUR

T1 - Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

AU - Baar, Marjolein

AU - Brandt, Renata

AU - Putavet, Diana

AU - Klein, Julian

AU - Derks, Kasper

AU - Bourgeois, BRM

AU - Stryeck, S

AU - Kamp, Yvonne

AU - Willigenburg, Hester

AU - Feijtel, Danny

AU - van der Pluijm, Ingrid

AU - Essers, J.

AU - van Cappellen, Gert

AU - van Ijcken, Wilfred

AU - Houtsmuller, Adriaan

AU - Pothof, Joris

AU - de Bruin, Ron

AU - Madl, T

AU - Hoeijmakers, Jan

AU - Campisi, J

AU - Keizer, Peter

PY - 2017

Y1 - 2017

U2 - 10.1016/j.cell.2017.02.031

DO - 10.1016/j.cell.2017.02.031

M3 - Article

C2 - 28340339

SN - 0092-8674

VL - 169

SP - 132

EP - 147

JO - Cell

JF - Cell

IS - 1

ER -