Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material

WWJ de Leng; CG Gadellaa - van Hooijdonk; F A S Barendregt-Smouter; MJ Koudijs; I Nijman; JWJ Hinrichs; E Cuppen; S van Lieshout; R D Loberg; Maja de Jonge; EE Voest; RA de Weger; N Steeghs; M H G Langenberg; Stefan Sleijfer; SM Willems; Martijn Lolkema

doi:10.1371/journal.pone.0149405

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material

WWJ de Leng, CG Gadellaa - van Hooijdonk, F A S Barendregt-Smouter, MJ Koudijs, I Nijman, JWJ Hinrichs, E Cuppen, S van Lieshout, R D Loberg, Maja de Jonge, EE Voest, RA de Weger, N Steeghs, M H G Langenberg, Stefan Sleijfer, SM Willems, Martijn Lolkema

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

81 Citations (Scopus)

30 Downloads (Pure)

Original language	Undefined/Unknown
Article number	e0149405
Journal	PLoS One (print)
Volume	11
Issue number	2
DOIs	https://doi.org/10.1371/journal.pone.0149405
Publication status	Published - 2016

Research programs

EMC MM-03-86-01
EMC MM-03-86-08

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Cite this

de Leng, WWJ., Gadellaa - van Hooijdonk, CG., Barendregt-Smouter, F. A. S., Koudijs, MJ., Nijman, I., Hinrichs, JWJ., Cuppen, E., van Lieshout, S., Loberg, R. D., de Jonge, M., Voest, EE., de Weger, RA., Steeghs, N., Langenberg, M. H. G., Sleijfer, S., Willems, SM., & Lolkema, M. (2016). Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material. PLoS One (print), 11(2), Article e0149405. https://doi.org/10.1371/journal.pone.0149405

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author = "{de Leng}, WWJ and {Gadellaa - van Hooijdonk}, CG and Barendregt-Smouter, {F A S} and MJ Koudijs and I Nijman and JWJ Hinrichs and E Cuppen and {van Lieshout}, S and Loberg, {R D} and {de Jonge}, Maja and EE Voest and {de Weger}, RA and N Steeghs and Langenberg, {M H G} and Stefan Sleijfer and SM Willems and Martijn Lolkema",

year = "2016",

doi = "10.1371/journal.pone.0149405",

language = "Undefined/Unknown",

volume = "11",

journal = "PLoS One (print)",

issn = "1932-6203",

publisher = "Public Library of Science",

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}

de Leng, WWJ, Gadellaa - van Hooijdonk, CG, Barendregt-Smouter, FAS, Koudijs, MJ, Nijman, I, Hinrichs, JWJ, Cuppen, E, van Lieshout, S, Loberg, RD, de Jonge, M, Voest, EE, de Weger, RA, Steeghs, N, Langenberg, MHG, Sleijfer, S, Willems, SM & Lolkema, M 2016, 'Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material', PLoS One (print), vol. 11, no. 2, e0149405. https://doi.org/10.1371/journal.pone.0149405

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material. / de Leng, WWJ; Gadellaa - van Hooijdonk, CG; Barendregt-Smouter, F A S et al.
In: PLoS One (print), Vol. 11, No. 2, e0149405, 2016.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - de Leng, WWJ

AU - Gadellaa - van Hooijdonk, CG

AU - Barendregt-Smouter, F A S

AU - Koudijs, MJ

AU - Nijman, I

AU - Hinrichs, JWJ

AU - Cuppen, E

AU - van Lieshout, S

AU - Loberg, R D

AU - de Jonge, Maja

AU - Voest, EE

AU - de Weger, RA

AU - Steeghs, N

AU - Langenberg, M H G

AU - Sleijfer, Stefan

AU - Willems, SM

AU - Lolkema, Martijn

PY - 2016

Y1 - 2016

U2 - 10.1371/journal.pone.0149405

DO - 10.1371/journal.pone.0149405

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de Leng WWJ, Gadellaa - van Hooijdonk CG, Barendregt-Smouter FAS, Koudijs MJ, Nijman I, Hinrichs JWJ et al. Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material. PLoS One (print). 2016;11(2):e0149405. doi: 10.1371/journal.pone.0149405