Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis

E Rees; N Carrera; J Morgan; K Hambridge; V Escott-Price; AJ Pocklington; AL Richards; AF Pardinas; C McDonald; G Donohoe; DW Morris; E Kenny; E Kelleher; M Gill; A Corvin; G Kirov; JTR Walters; P Holmans; MJ Owen; MC O'Donovan; BZ Alizadeh; T van Amelsvoort; AA Bartels-Velthuis; JM Beveren; R Bruggeman; W Cahn; L de Haan; P Delespaul; CJ Meijer; I Myin-Germeys; RS Kahn; F Schirmbeck; CJP Simons; NE van Haren; J van Os; R van Winkel; JJ Luykx

doi:10.1016/j.biopsych.2018.08.022

Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis

E Rees, N Carrera, J Morgan, K Hambridge, V Escott-Price, AJ Pocklington, AL Richards, AF Pardinas, C McDonald, G Donohoe, DW Morris, E Kenny, E Kelleher, M Gill, A Corvin, G Kirov, JTR Walters, P Holmans, MJ Owen, MC O'DonovanBZ Alizadeh, T van Amelsvoort, AA Bartels-Velthuis, JM Beveren, R Bruggeman, W Cahn, L de Haan, P Delespaul, CJ Meijer, I Myin-Germeys, RS Kahn, F Schirmbeck, CJP Simons, NE van Haren, J van Os, R van Winkel, JJ Luykx

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

23 Downloads (Pure)

Original language	Undefined/Unknown
Pages (from-to)	554-562
Number of pages	9
Journal	Biological Psychiatry
Volume	85
Issue number	7
DOIs	https://doi.org/10.1016/j.biopsych.2018.08.022
Publication status	Published - 2019

Research programs

EMC ONWAR-01-58-02

Access to Document

10.1016/j.biopsych.2018.08.022

Repub-116157-OA.pdfFinal published version, 332 KB

http://hdl.handle.net/1765/116157

Cite this

Rees, E., Carrera, N., Morgan, J., Hambridge, K., Escott-Price, V., Pocklington, AJ., Richards, AL., Pardinas, AF., McDonald, C., Donohoe, G., Morris, DW., Kenny, E., Kelleher, E., Gill, M., Corvin, A., Kirov, G., Walters, JTR., Holmans, P., Owen, MJ., ... Luykx, JJ. (2019). Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis. Biological Psychiatry, 85(7), 554-562. https://doi.org/10.1016/j.biopsych.2018.08.022

@article{7f7fcb2afc6b4fef941a216fd787aa51,

title = "Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis",

author = "E Rees and N Carrera and J Morgan and K Hambridge and V Escott-Price and AJ Pocklington and AL Richards and AF Pardinas and C McDonald and G Donohoe and DW Morris and E Kenny and E Kelleher and M Gill and A Corvin and G Kirov and JTR Walters and P Holmans and MJ Owen and MC O'Donovan and BZ Alizadeh and {van Amelsvoort}, T and AA Bartels-Velthuis and JM Beveren and R Bruggeman and W Cahn and {de Haan}, L and P Delespaul and CJ Meijer and I Myin-Germeys and RS Kahn and F Schirmbeck and CJP Simons and {van Haren}, NE and {van Os}, J and {van Winkel}, R and JJ Luykx",

year = "2019",

doi = "10.1016/j.biopsych.2018.08.022",

language = "Undefined/Unknown",

volume = "85",

pages = "554--562",

journal = "Biological Psychiatry",

issn = "0006-3223",

publisher = "Elsevier Inc.",

number = "7",

}

Rees, E, Carrera, N, Morgan, J, Hambridge, K, Escott-Price, V, Pocklington, AJ, Richards, AL, Pardinas, AF, McDonald, C, Donohoe, G, Morris, DW, Kenny, E, Kelleher, E, Gill, M, Corvin, A, Kirov, G, Walters, JTR, Holmans, P, Owen, MJ, O'Donovan, MC, Alizadeh, BZ, van Amelsvoort, T, Bartels-Velthuis, AA, Beveren, JM, Bruggeman, R, Cahn, W, de Haan, L, Delespaul, P, Meijer, CJ, Myin-Germeys, I, Kahn, RS, Schirmbeck, F, Simons, CJP, van Haren, NE, van Os, J, van Winkel, R & Luykx, JJ 2019, 'Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis', Biological Psychiatry, vol. 85, no. 7, pp. 554-562. https://doi.org/10.1016/j.biopsych.2018.08.022

TY - JOUR

T1 - Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis

AU - Rees, E

AU - Carrera, N

AU - Morgan, J

AU - Hambridge, K

AU - Escott-Price, V

AU - Pocklington, AJ

AU - Richards, AL

AU - Pardinas, AF

AU - McDonald, C

AU - Donohoe, G

AU - Morris, DW

AU - Kenny, E

AU - Kelleher, E

AU - Gill, M

AU - Corvin, A

AU - Kirov, G

AU - Walters, JTR

AU - Holmans, P

AU - Owen, MJ

AU - O'Donovan, MC

AU - Alizadeh, BZ

AU - van Amelsvoort, T

AU - Bartels-Velthuis, AA

AU - Beveren, JM

AU - Bruggeman, R

AU - Cahn, W

AU - de Haan, L

AU - Delespaul, P

AU - Meijer, CJ

AU - Myin-Germeys, I

AU - Kahn, RS

AU - Schirmbeck, F

AU - Simons, CJP

AU - van Haren, NE

AU - van Os, J

AU - van Winkel, R

AU - Luykx, JJ

PY - 2019

Y1 - 2019

U2 - 10.1016/j.biopsych.2018.08.022

DO - 10.1016/j.biopsych.2018.08.022

M3 - Article

C2 - 30420267

SN - 0006-3223

VL - 85

SP - 554

EP - 562

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 7

ER -