Temporary Right Ventricular Assist Devices: A Systematic Review

Mahmoud Abdelshafy, Kadir Caliskan, Goksel Guven, Ahmed Elkoumy, Hagar Elsherbini, Hesham Elzomor, Erhan Tenekecioglu, Sakir Akin, Osama Soliman*

*Corresponding author for this work

Research output: Contribution to journalReview articlePopular

1 Citation (Scopus)
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Abstract

Acute right-sided heart failure (RHF) is a complex clinical syndrome, with a wide range of clinical presentations, associated with increased mortality and morbidity, but about which there is a scarcity of evidence-based literature. A temporary right ventricular assist device (t-RVAD) is a potential treatment option for selected patients with severe right ventricular dysfunction as a bridge-to-recovery or as a permanent solution. We sought to conduct a systematic review to determine the safety and efficacy of t-RVAD implantation. Thirty-one studies met the inclusion criteria, from which data were extracted. Successful t-RVAD weaning ranged between 23% and 100%. Moreover, 30-day survival post-temporary RAVD implantation ranged from 46% to 100%. Bleeding, acute kidney injury, stroke, and device malfunction were the most commonly reported complications. Notwithstanding this, t-RVAD is a lifesaving option for patients with severe RHF, but the evidence stems from small non-randomized heterogeneous studies utilizing a variety of devices. Both the etiology of RHF and time of intervention might play a major role in determining the t-RVAD outcome. Standardized endpoints definitions, design and methodology for t-RVAD trials is needed. Furthermore, efforts should continue in improving the technology as well as improving the timely provision of a t-RVAD.

Original languageEnglish
Article number613
JournalJournal of Clinical Medicine
Volume11
Issue number3
DOIs
Publication statusPublished - 26 Jan 2022

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© 2022 by the authors. Licensee MDPI, Basel, Switzerland.

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