The alpha2-macroglobulin gene in AD: A population-based study and meta-analysis

M.N. Koster, B. Dermaut, M. Cruts, J.J. Houwing-Duistermaat, Gerwin Roks, J. Tol, A. Ott, Bert Hofman, G. Munteanu, Monique Breteler, Cornelia Duijn, C. van Broeckhoven

Research output: Contribution to journalArticleAcademicpeer-review

59 Citations (Scopus)

Abstract

The results suggest that A2M is not genetically associated with LOAD in white patients or mixed populations as found in the United States. In these populations A2M does not have clinical relevance. From a scientific perspective, the findings on EOAD and Asian patients require replication and further research in the A2M region.
Original languageEnglish
Pages (from-to)678-684
Number of pages7
JournalNeurology
Volume55
Issue number5
DOIs
Publication statusPublished - 12 Sept 2000

Research programs

  • EMC NIHES-01-64-02

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