The Angiotensin II Type 2 Receptor for Pain Control

Jan Danser; P Anand

doi:10.1016/j.cell.2014.05.030

The Angiotensin II Type 2 Receptor for Pain Control

Jan Danser
, P Anand

Internal Medicine

Research output: Contribution to journal › Article › Academic › peer-review

29 Citations (Scopus)

Abstract

All well-known deleterious effects of angiotensin (Ang) II, including vasoconstriction, inflammation, water and salt retention, and vascular remodeling, are mediated via its type 1 (AT(1)) receptor. This explains why AT(1) receptor blockers (ARBs) and inhibitors of Ang II synthesis, such as ACE inhibitors and renin inhibitors, are beneficial for cardiovascular disease. Yet, Ang II has a second receptor, the Ang II type 2 (AT(2)) receptor, the function of which, even after over 20 years of research, remains largely unknown. In this issue, Marion et al. provide a new chapter to the AT(2) receptor story.

Original language	Undefined/Unknown
Pages (from-to)	1504-1506
Number of pages	3
Journal	Cell
Volume	157
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2014.05.030
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research programs

EMC COEUR-09

Access to Document

10.1016/j.cell.2014.05.030

http://hdl.handle.net/1765/81473

Cite this

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