The application of multiplexed assay systems for molecular diagnostics

E Schwarz, JM Beveren, PC Guest, R Izmailov, Sabine Bahn

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

For decades, the diagnosis of schizophrenia and other psychiatric disorders has relied on subjective assessments such as Diagnostic and Statistical Manual criteria. There is now increasing interest in the identification of altered molecular patterns in blood and other accessible body fluids that can be used to help identify, stratify and monitor psychiatric patients. Since shorter periods of psychosis are associated with a better prognosis, an accurate molecular test may lead to early intervention and thereby improve patient outcomes. In addition, such a test would open up the possibility to stratify more accurately the disease and could represent a novel translational medicine tool, which is crucial for the discovery and development of more efficacious therapies.
Original languageUndefined/Unknown
Pages (from-to)259-278
Number of pages20
JournalInternational Review of Neurobiology
Volume101
DOIs
Publication statusPublished - 2011

Research programs

  • EMC OR-01-58-01

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