The association between cigarette smoking and multiple sclerosis

Naghmeh Jafari; Rogier Hintzen

doi:10.1016/j.jns.2011.09.008

The association between cigarette smoking and multiple sclerosis

Naghmeh Jafari, Rogier Hintzen

Neurology

Research output: Contribution to journal › Article › Academic › peer-review

36 Citations (Scopus)

Abstract

Genetic factors partially explain the susceptibility of multiple sclerosis (MS) and might even relate to the clinical course. Still, many epidemiological studies point at an important role for environmental factors in MS. Smoking is one of the major candidates. In this review we provide an overview of the epidemiological studies on cigarette smoking and the association on MS risk and MS clinical course. In addition, we discuss the possible biological pathways that may influence neurological damage in MS. Moreover, the relation of smoking with other environmental MS risk factors will be addressed. (C) 2011 Elsevier B.V. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	78-85
Number of pages	8
Journal	Journal of the Neurological Sciences
Volume	311
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jns.2011.09.008
Publication status	Published - 2011

Research programs

EMC MM-04-44-02

Access to Document

10.1016/j.jns.2011.09.008

http://hdl.handle.net/1765/33170

Cite this

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title = "The association between cigarette smoking and multiple sclerosis",

abstract = "Genetic factors partially explain the susceptibility of multiple sclerosis (MS) and might even relate to the clinical course. Still, many epidemiological studies point at an important role for environmental factors in MS. Smoking is one of the major candidates. In this review we provide an overview of the epidemiological studies on cigarette smoking and the association on MS risk and MS clinical course. In addition, we discuss the possible biological pathways that may influence neurological damage in MS. Moreover, the relation of smoking with other environmental MS risk factors will be addressed. (C) 2011 Elsevier B.V. All rights reserved.",

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