The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study

M M A van Buuren; J J Heerey; A Smith; K M Crossley; J L Kemp; M J Scholes; P R Lawrenson; M G King; W P Gielis; H Weinans; C Lindner; R B Souza; J A N Verhaar; R Agricola

doi:10.1016/j.ocarto.2022.100275

The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study

M M A van Buuren^*, J J Heerey, A Smith, K M Crossley, J L Kemp, M J Scholes, P R Lawrenson, M G King, W P Gielis, H Weinans, C Lindner, R B Souza, J A N Verhaar, R Agricola

^*Corresponding author for this work

Orthopedics and Sports Medicine

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

67 Downloads (Pure)

Abstract

OBJECTIVE: To explore the relationship between radiographic hip shape and features of early hip osteoarthritis (OA) on magnetic resonance imaging (MRI) in young male and female football players without radiographic hip OA.

DESIGN: We used baseline data from a cohort of symptomatic and asymptomatic football players aged 18-50 years. Hip shape was assessed on anteroposterior radiographs with statistical shape modeling (SSM) for men and women separately. Cartilage defects and labral tears were graded using the Scoring Hip Osteoarthritis with MRI (SHOMRI) system. We used logistic regression with generalized estimating equations to estimate associations between each hip shape variant, called shape modes, and cartilage defects or labral tears.

RESULTS: We included 229 participants (446 hips, 77.4% male). For each sex, 15 shape modes were analyzed. In men, three shape modes were associated with cartilage defects: adjusted odds ratios (aOR) 0.75 (95%CI 0.58-0.97) per standard deviation (SD) for mode 1; 1.34 (95%CI 1.05-1.69) per SD for mode 12; and 0.61 (95%CI 0.48-0.78) per SD for mode 15; and one also with labral tears: aOR 1.30 (95%CI 1.01-1.69) per SD for mode 12. These modes generally represented variations in the femoral neck and subtypes of cam morphology, with and without pincer morphology. For women, there was no evidence for associations with the outcomes.

CONCLUSIONS: Several hip shape variants were associated with cartilage defects on MRI in young male football players. Specifically, one subtype of cam morphology was associated with both cartilage defects and labral tears. Hip shape was not associated with early OA features in women.

Original language	English
Article number	100275
Journal	Osteoarthritis and Cartilage Open
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.ocarto.2022.100275
Publication status	Published - Sept 2022

Bibliographical note

Role of the funding source:
The study was supported by a National Health and Medical Research
Council of Australia (NHMRC) project grant (GNT1088683). The funding
body did not have a role in study design, collection, analysis and interpretation of data, writing of the manuscript or decision to submit the
manuscript for publication.

© 2022 The Authors.

Access to Document

10.1016/j.ocarto.2022.100275Licence: CC BY

The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football playersFinal published version, 434 KBLicence: CC BY

Fingerprint

Dive into the research topics of 'The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study'. Together they form a unique fingerprint.

Cite this

van Buuren, M. M. A., Heerey, J. J., Smith, A., Crossley, K. M., Kemp, J. L., Scholes, M. J., Lawrenson, P. R., King, M. G., Gielis, W. P., Weinans, H., Lindner, C., Souza, R. B., Verhaar, J. A. N., & Agricola, R. (2022). The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study. Osteoarthritis and Cartilage Open, 4(3), Article 100275. https://doi.org/10.1016/j.ocarto.2022.100275

@article{1511c75fd9124ac8994e4b1efcba6cad,

title = "The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study",

abstract = "OBJECTIVE: To explore the relationship between radiographic hip shape and features of early hip osteoarthritis (OA) on magnetic resonance imaging (MRI) in young male and female football players without radiographic hip OA.DESIGN: We used baseline data from a cohort of symptomatic and asymptomatic football players aged 18-50 years. Hip shape was assessed on anteroposterior radiographs with statistical shape modeling (SSM) for men and women separately. Cartilage defects and labral tears were graded using the Scoring Hip Osteoarthritis with MRI (SHOMRI) system. We used logistic regression with generalized estimating equations to estimate associations between each hip shape variant, called shape modes, and cartilage defects or labral tears.RESULTS: We included 229 participants (446 hips, 77.4\% male). For each sex, 15 shape modes were analyzed. In men, three shape modes were associated with cartilage defects: adjusted odds ratios (aOR) 0.75 (95\%CI 0.58-0.97) per standard deviation (SD) for mode 1; 1.34 (95\%CI 1.05-1.69) per SD for mode 12; and 0.61 (95\%CI 0.48-0.78) per SD for mode 15; and one also with labral tears: aOR 1.30 (95\%CI 1.01-1.69) per SD for mode 12. These modes generally represented variations in the femoral neck and subtypes of cam morphology, with and without pincer morphology. For women, there was no evidence for associations with the outcomes.CONCLUSIONS: Several hip shape variants were associated with cartilage defects on MRI in young male football players. Specifically, one subtype of cam morphology was associated with both cartilage defects and labral tears. Hip shape was not associated with early OA features in women.",

author = "\{van Buuren\}, \{M M A\} and Heerey, \{J J\} and A Smith and Crossley, \{K M\} and Kemp, \{J L\} and Scholes, \{M J\} and Lawrenson, \{P R\} and King, \{M G\} and Gielis, \{W P\} and H Weinans and C Lindner and Souza, \{R B\} and Verhaar, \{J A N\} and R Agricola",

note = "Role of the funding source: The study was supported by a National Health and Medical Research Council of Australia (NHMRC) project grant (GNT1088683). The funding body did not have a role in study design, collection, analysis and interpretation of data, writing of the manuscript or decision to submit the manuscript for publication. {\textcopyright} 2022 The Authors.",

year = "2022",

month = sep,

doi = "10.1016/j.ocarto.2022.100275",

language = "English",

volume = "4",

journal = "Osteoarthritis and Cartilage Open",

issn = "2665-9131",

publisher = "Elsevier Ltd.",

number = "3",

}

van Buuren, MMA, Heerey, JJ, Smith, A, Crossley, KM, Kemp, JL, Scholes, MJ, Lawrenson, PR, King, MG, Gielis, WP, Weinans, H, Lindner, C, Souza, RB, Verhaar, JAN & Agricola, R 2022, 'The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study', Osteoarthritis and Cartilage Open, vol. 4, no. 3, 100275. https://doi.org/10.1016/j.ocarto.2022.100275

The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study. / van Buuren, M M A; Heerey, J J; Smith, A et al.
In: Osteoarthritis and Cartilage Open, Vol. 4, No. 3, 100275, 09.2022.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players

T2 - Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study

AU - van Buuren, M M A

AU - Heerey, J J

AU - Smith, A

AU - Crossley, K M

AU - Kemp, J L

AU - Scholes, M J

AU - Lawrenson, P R

AU - King, M G

AU - Gielis, W P

AU - Weinans, H

AU - Lindner, C

AU - Souza, R B

AU - Verhaar, J A N

AU - Agricola, R

N1 - Role of the funding source: The study was supported by a National Health and Medical Research Council of Australia (NHMRC) project grant (GNT1088683). The funding body did not have a role in study design, collection, analysis and interpretation of data, writing of the manuscript or decision to submit the manuscript for publication. © 2022 The Authors.

PY - 2022/9

Y1 - 2022/9

N2 - OBJECTIVE: To explore the relationship between radiographic hip shape and features of early hip osteoarthritis (OA) on magnetic resonance imaging (MRI) in young male and female football players without radiographic hip OA.DESIGN: We used baseline data from a cohort of symptomatic and asymptomatic football players aged 18-50 years. Hip shape was assessed on anteroposterior radiographs with statistical shape modeling (SSM) for men and women separately. Cartilage defects and labral tears were graded using the Scoring Hip Osteoarthritis with MRI (SHOMRI) system. We used logistic regression with generalized estimating equations to estimate associations between each hip shape variant, called shape modes, and cartilage defects or labral tears.RESULTS: We included 229 participants (446 hips, 77.4% male). For each sex, 15 shape modes were analyzed. In men, three shape modes were associated with cartilage defects: adjusted odds ratios (aOR) 0.75 (95%CI 0.58-0.97) per standard deviation (SD) for mode 1; 1.34 (95%CI 1.05-1.69) per SD for mode 12; and 0.61 (95%CI 0.48-0.78) per SD for mode 15; and one also with labral tears: aOR 1.30 (95%CI 1.01-1.69) per SD for mode 12. These modes generally represented variations in the femoral neck and subtypes of cam morphology, with and without pincer morphology. For women, there was no evidence for associations with the outcomes.CONCLUSIONS: Several hip shape variants were associated with cartilage defects on MRI in young male football players. Specifically, one subtype of cam morphology was associated with both cartilage defects and labral tears. Hip shape was not associated with early OA features in women.

AB - OBJECTIVE: To explore the relationship between radiographic hip shape and features of early hip osteoarthritis (OA) on magnetic resonance imaging (MRI) in young male and female football players without radiographic hip OA.DESIGN: We used baseline data from a cohort of symptomatic and asymptomatic football players aged 18-50 years. Hip shape was assessed on anteroposterior radiographs with statistical shape modeling (SSM) for men and women separately. Cartilage defects and labral tears were graded using the Scoring Hip Osteoarthritis with MRI (SHOMRI) system. We used logistic regression with generalized estimating equations to estimate associations between each hip shape variant, called shape modes, and cartilage defects or labral tears.RESULTS: We included 229 participants (446 hips, 77.4% male). For each sex, 15 shape modes were analyzed. In men, three shape modes were associated with cartilage defects: adjusted odds ratios (aOR) 0.75 (95%CI 0.58-0.97) per standard deviation (SD) for mode 1; 1.34 (95%CI 1.05-1.69) per SD for mode 12; and 0.61 (95%CI 0.48-0.78) per SD for mode 15; and one also with labral tears: aOR 1.30 (95%CI 1.01-1.69) per SD for mode 12. These modes generally represented variations in the femoral neck and subtypes of cam morphology, with and without pincer morphology. For women, there was no evidence for associations with the outcomes.CONCLUSIONS: Several hip shape variants were associated with cartilage defects on MRI in young male football players. Specifically, one subtype of cam morphology was associated with both cartilage defects and labral tears. Hip shape was not associated with early OA features in women.

UR - https://www.scopus.com/pages/publications/85162305198

U2 - 10.1016/j.ocarto.2022.100275

DO - 10.1016/j.ocarto.2022.100275

M3 - Article

C2 - 36474944

SN - 2665-9131

VL - 4

JO - Osteoarthritis and Cartilage Open

JF - Osteoarthritis and Cartilage Open

IS - 3

M1 - 100275

ER -

van Buuren MMA, Heerey JJ, Smith A, Crossley KM, Kemp JL, Scholes MJ et al. The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study. Osteoarthritis and Cartilage Open. 2022 Sept;4(3):100275. doi: 10.1016/j.ocarto.2022.100275

The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this