@inproceedings{2a255cd94158465c960510f4ea300248,
title = "The clinical translation of a near-infrared fluorophore for fluorescence guided surgery: SGM-101 from the lab to a phase III trial",
abstract = "Near-infrared (NIR) fluorescence imaging is a promising intraoperative technique for real-time visualization of tumor ti{\ss}ue during surgery. The proce{\ss} of clinical translation of novel fluorescent agents is an e{\ss}ential part in the evolution of NIR fluorescence guided surgery. Poor visualization of tumors during surgery is one of the major challenges surgeons often face in oncologic patients, mainly due to the improved neo-adjuvant treatment patients receive. In these cases, NIR fluorescence imaging with the use of tumor-targeted fluorescent agents can play an e{\ss}ential role and help provide better oncologic results or patient outcomes. However, before this technique can be implemented in standard of care, optimal tumor-targeted fluorescent agents need to be developed and novel fluorescent agents need to undergo a succe{\ss}ful proce{\ss} of clinical translation. Here we describe the clinical translation of SGM-101, a fluorescent anti-CEA monoclonal antibody.",
author = "Meijer, {Ruben P.J.} and {De Valk}, {Kim S.} and B{\'e}r{\'e}nice Framery and Marian Gutowski and Andr{\'e} P{\`e}legrin and Fran{\c c}oise Cailler and Hilling, {Denise E.} and Vahrmeijer, {Alexander L.}",
note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Molecular-Guided Surgery: Molecules, Devices, and Applications VI 2020 ; Conference date: 01-02-2020 Through 02-02-2020",
year = "2020",
doi = "10.1117/12.2555598",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Sylvain Gioux and Gibbs, {Summer L.} and Pogue, {Brian W.}",
booktitle = "Molecular-Guided Surgery",
address = "United States",
}