The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

M Barazas; S Annunziato; SJ Pettitt; I de Krijger; H Ghezraoui; Stefan Roobol; C Lutz; J Frankum; FF Song; R Brough; B Evers; E Gogola; J Bhin; M Ven; Dik van Gent; JJL Jacobs; R Chapman; CJ Lord; J Jonkers; S Rottenberg

doi:10.1016/j.celrep.2018.04.046

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

M Barazas
, S Annunziato
, SJ Pettitt
, I de Krijger
, H Ghezraoui
, Stefan Roobol
, C Lutz
, J Frankum
, FF Song
, R Brough
, B Evers
, E Gogola
, J Bhin
, M Ven
, Dik van Gent
, JJL Jacobs
, R Chapman
, CJ Lord
, J Jonkers
, S Rottenberg

Research output: Contribution to journal › Article › Academic

130 Citations (Scopus)

84 Downloads (Pure)

Original language	Undefined/Unknown
Pages (from-to)	2107-2118
Number of pages	12
Journal	Cell Reports
Volume	23
Issue number	7
DOIs	https://doi.org/10.1016/j.celrep.2018.04.046
Publication status	Published - 2018

Research programs

EMC NIHES-03-30-03

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10.1016/j.celrep.2018.04.046

The-CST-Complex-Mediates-End-Protection.pdfFinal published version, 3.24 MB

http://hdl.handle.net/1765/106351

Cite this

Barazas, M., Annunziato, S., Pettitt, SJ., de Krijger, I., Ghezraoui, H., Roobol, S., Lutz, C., Frankum, J., Song, FF., Brough, R., Evers, B., Gogola, E., Bhin, J., Ven, M., van Gent, D., Jacobs, JJL., Chapman, R., Lord, CJ., Jonkers, J., & Rottenberg, S. (2018). The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells. Cell Reports, 23(7), 2107-2118. https://doi.org/10.1016/j.celrep.2018.04.046

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title = "The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells",

author = "M Barazas and S Annunziato and SJ Pettitt and \{de Krijger\}, I and H Ghezraoui and Stefan Roobol and C Lutz and J Frankum and FF Song and R Brough and B Evers and E Gogola and J Bhin and M Ven and \{van Gent\}, Dik and JJL Jacobs and R Chapman and CJ Lord and J Jonkers and S Rottenberg",

year = "2018",

doi = "10.1016/j.celrep.2018.04.046",

language = "Undefined/Unknown",

volume = "23",

pages = "2107--2118",

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Barazas, M, Annunziato, S, Pettitt, SJ, de Krijger, I, Ghezraoui, H, Roobol, S, Lutz, C, Frankum, J, Song, FF, Brough, R, Evers, B, Gogola, E, Bhin, J, Ven, M, van Gent, D, Jacobs, JJL, Chapman, R, Lord, CJ, Jonkers, J & Rottenberg, S 2018, 'The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells', Cell Reports, vol. 23, no. 7, pp. 2107-2118. https://doi.org/10.1016/j.celrep.2018.04.046

TY - JOUR

T1 - The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

AU - Barazas, M

AU - Annunziato, S

AU - Pettitt, SJ

AU - de Krijger, I

AU - Ghezraoui, H

AU - Roobol, Stefan

AU - Lutz, C

AU - Frankum, J

AU - Song, FF

AU - Brough, R

AU - Evers, B

AU - Gogola, E

AU - Bhin, J

AU - Ven, M

AU - van Gent, Dik

AU - Jacobs, JJL

AU - Chapman, R

AU - Lord, CJ

AU - Jonkers, J

AU - Rottenberg, S

PY - 2018

Y1 - 2018

U2 - 10.1016/j.celrep.2018.04.046

DO - 10.1016/j.celrep.2018.04.046

M3 - Article

C2 - 29768208

SN - 2211-1247

VL - 23

SP - 2107

EP - 2118

JO - Cell Reports

JF - Cell Reports

IS - 7

ER -