The danish diabetes musculoskeletal cohort: Non-responder analysis of an electronic survey using registry data

Eleanor Boyle, Lars Folkestad, Erik Frafjord, Bart W. Koes, Soren Thorgaard Skou, Jan Hartvigsen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Purpose: To conduct a non-responder analysis on a musculoskeletal (MSK) electronic questionnaire. 

Methods: Individuals aged 18 years and older, diagnosed with diabetes mellitus (DM), and attended an ambulatory DM clinic formed the sample frame. They were invited to complete an electronic musculoskeletal (MSK) conditions and symptoms questionnaire booklet using a secured electronic email system. Individuals whose secured email box was not active at the time were discarded. Using the Central Person Registry number, a unique number assigned to all Danish residents, we linked the sample frame to different registries to learn more about non-responders. Non-responders were either individuals who did not respond to a single question and those who responded “No” to the first question about willing to participate. We calculated descriptive statistics for each characteristic. Univariate logistic regression models were conducted to determine the relationship between each characteristic and non-responder status. 

Results: The response rate was 36% (n = 3812). Individuals with type 2 DM (OR 2.0 (95% CI 1.8-2.2)), secondary DM (1.9 (1.3-2.8)) or unspecified DM (2.1 (1.8-2.4)) were more likely to be non-responders than individuals with Type 1 DM. Also, individuals aged 70-79 (1.3 (1.1-1.6)) and 80 years and older (5.9 (4.5-7.7)) were more likely to be non-responders than 18-29 years old individuals. However, individuals aged 40-49 (1.5 (1.2-1.8)), 50-59 (1.5 (1.3-1.8)) or 60-69 (1.4 (1.1-1.6)) were more likely to be responders than 18-29 years old individuals. Individuals with Charlson Comorbidity Index (CCI) of 1 (2.0 (1.3.2.9) or CCI of 2 (1.7 (1.1-2.5) were more likely to be responders than individuals with a CCI of 0. Lastly, individuals who were currently outside of the workforce (1.6 (2.4-2.9) or had unknown/missing socioeconomic status (3.9 (2.8-5.3) were more likely to be non- responders than individuals who were working. 

Conclusion: Although we did find a non-response bias, this cohort will be an important source to determine the prevalence and consequences of MSK conditions in a secondary care DM population.

Original languageEnglish
Pages (from-to)397-405
Number of pages9
JournalClinical Epidemiology
Volume13
DOIs
Publication statusPublished - 31 May 2021

Bibliographical note

Funding Information:
Erik Frafjord was funded by a grant from the Danish Foundation for Chiropractic Research and Postgraduate Education.Søren Skou is currently funded by a grant from the European Research Council (ERC) under the European Union’ s Horizon 2020 research and innovation program (grant agreement No 801790) and a program grant from Region Zealand (Exercise First).The Department of Endocrinology , Odense University Hospital, funded expenses related to study administration and expenses related to Statistics Denmark.

Publisher Copyright:
© 2021 Boyle et al.

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