The development of a screening tool to identify and classify nonadherence in inflammatory bowel disease

Aria Zand; Audrey Nguyen; Zack Stokes; Welmoed van Deen; Courtney Reynolds; Magdalena Dimitrova; Ariela Khandadash; Miriam Dvorsky; Jenny Sauk; Eric Esrailian; Daniel Hommes

doi:10.1093/crocol/otz035

The development of a screening tool to identify and classify nonadherence in inflammatory bowel disease

Aria Zand^*
, Audrey Nguyen
, Zack Stokes
, Welmoed van Deen
, Courtney Reynolds
, Magdalena Dimitrova
, Ariela Khandadash
, Miriam Dvorsky
, Jenny Sauk
, Eric Esrailian
, Daniel Hommes

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

6 Downloads (Pure)

Abstract

Background:

Medication nonadherence is a challenge in chronic disease management. Tools that can both determine adherence levels and analyze patient-specific reasons for nonadherence are lacking.

Methods:

Our tool was developed using 23 patient-reported items and its predictive performance was compared with the most widely used instrument in the literature.

Results:

One hundred thirty-three IBD patients were included, 44 (33%) were nonadherent and 89 (67%) were adherent. Our screening question, with 87% sensitivity and 64% specificity, was followed by a 9-item survey for patients qualified as nonadherent.

Conclusions:

Quantifying reasons for nonadherence can lead to more effective and personalized interventions for nonadherent patients. Medication nonadherence means that patients do not take medications as instructed by their physician. Our study created a short screening questionnaire to find out why patients with IBD might not take their medication.

Original language	English
Journal	Crohn's and Colitis 360
Volume	1
Issue number	3
DOIs	https://doi.org/10.1093/crocol/otz035
Publication status	Published - Oct 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2019 Crohn's & Colitis Foundation. Published by Oxford University Press on behalf of Crohn's & Colitis Foundation.

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10.1093/crocol/otz035Licence: CC BY-NC

The Development of a Screening Tool to Identify and Classify Nonadherence in Inflammatory Bowel DiseaseFinal published version, 202 KBLicence: CC BY-NC

Cite this

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title = "The development of a screening tool to identify and classify nonadherence in inflammatory bowel disease",

abstract = "Background: Medication nonadherence is a challenge in chronic disease management. Tools that can both determine adherence levels and analyze patient-specific reasons for nonadherence are lacking. Methods: Our tool was developed using 23 patient-reported items and its predictive performance was compared with the most widely used instrument in the literature. Results: One hundred thirty-three IBD patients were included, 44 (33\%) were nonadherent and 89 (67\%) were adherent. Our screening question, with 87\% sensitivity and 64\% specificity, was followed by a 9-item survey for patients qualified as nonadherent. Conclusions: Quantifying reasons for nonadherence can lead to more effective and personalized interventions for nonadherent patients. Medication nonadherence means that patients do not take medications as instructed by their physician. Our study created a short screening questionnaire to find out why patients with IBD might not take their medication.",

author = "Aria Zand and Audrey Nguyen and Zack Stokes and \{van Deen\}, Welmoed and Courtney Reynolds and Magdalena Dimitrova and Ariela Khandadash and Miriam Dvorsky and Jenny Sauk and Eric Esrailian and Daniel Hommes",

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doi = "10.1093/crocol/otz035",

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T1 - The development of a screening tool to identify and classify nonadherence in inflammatory bowel disease

AU - Zand, Aria

AU - Nguyen, Audrey

AU - Stokes, Zack

AU - van Deen, Welmoed

AU - Reynolds, Courtney

AU - Dimitrova, Magdalena

AU - Khandadash, Ariela

AU - Dvorsky, Miriam

AU - Sauk, Jenny

AU - Esrailian, Eric

AU - Hommes, Daniel

PY - 2019/10

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N2 - Background: Medication nonadherence is a challenge in chronic disease management. Tools that can both determine adherence levels and analyze patient-specific reasons for nonadherence are lacking. Methods: Our tool was developed using 23 patient-reported items and its predictive performance was compared with the most widely used instrument in the literature. Results: One hundred thirty-three IBD patients were included, 44 (33%) were nonadherent and 89 (67%) were adherent. Our screening question, with 87% sensitivity and 64% specificity, was followed by a 9-item survey for patients qualified as nonadherent. Conclusions: Quantifying reasons for nonadherence can lead to more effective and personalized interventions for nonadherent patients. Medication nonadherence means that patients do not take medications as instructed by their physician. Our study created a short screening questionnaire to find out why patients with IBD might not take their medication.

AB - Background: Medication nonadherence is a challenge in chronic disease management. Tools that can both determine adherence levels and analyze patient-specific reasons for nonadherence are lacking. Methods: Our tool was developed using 23 patient-reported items and its predictive performance was compared with the most widely used instrument in the literature. Results: One hundred thirty-three IBD patients were included, 44 (33%) were nonadherent and 89 (67%) were adherent. Our screening question, with 87% sensitivity and 64% specificity, was followed by a 9-item survey for patients qualified as nonadherent. Conclusions: Quantifying reasons for nonadherence can lead to more effective and personalized interventions for nonadherent patients. Medication nonadherence means that patients do not take medications as instructed by their physician. Our study created a short screening questionnaire to find out why patients with IBD might not take their medication.

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DO - 10.1093/crocol/otz035

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JO - Crohn's and Colitis 360

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ER -

The development of a screening tool to identify and classify nonadherence in inflammatory bowel disease

Abstract

Bibliographical note

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