The effect of canola, sesame and sesame-canola oils on body fat and composition in adults: a triple-blind, three-way randomised cross-over clinical trial

Fatemeh Moghtaderi, Mojgan Amiri, Alireza Zimorovat, Hamidreza Raeisi-Dehkordi, Masoud Rahmanian, Mahdieh Hosseinzadeh, Hossein Fallahzadeh, Amin Salehi-Abargouei*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)


The present study aimed to examine the effect of replacing edible oils with sesame oil (SO), canola oil (CO) and sesame-canola oil (SCO) on body weight and composition in adults. Adults without any chronic diseases (n = 77) were entered a 4-week run-in period and then were randomised to receive SO, CO and SCO for their household use in 9-week intervention periods (separated by 4-week washout intervals). Anthropometric measurements, as well as body composition markers, were assessed at baseline, middle and after each intervention period. In total, 73 participants completed the study. Although significant time effects were seen for waist and hip circumference, waist-to-hip ratio, central obesity index, body adiposity index, muscle mass and body fat percent (p time<.05), the treatment and treatment × time effects were not significant (p>.05). The present clinical trial revealed that CO, SO and SCO might not differently affect body fat and composition. Trial registration code: IRCT2016091312571N6 (

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalInternational Journal of Food Sciences and Nutrition
Issue number2
Publication statusPublished - 2020
Externally publishedYes

Bibliographical note

Funding Information:
The study received funding from Shahid Sadoughi University of Medical sciences and Datis Corporation. The Datis Corporation did not take any part in the conception, design, the execution of the study protocol, and the reporting of the study results. The corporation did not have any other relationship with the investigators. The authors assert that they have no other potential personal or financial conflicts of interest. The principal investigator (ASA) declares that he has full access to the data and samples provided by this project.

Funding Information:
The study was supported by Shahid Sadoughi University of Medical Sciences ( and Neshatavar Food Industry (Datis Corporation) ( The authors appreciate all the subjects for their voluntary and enthusiastic involvement in the study. Furthermore, the scientific support of the research council of Nutrition and Food Security Research Center is highly appreciated. The authors are also grateful to the diabetes research center of Shahid Sadoughi University of Medical Sciences, Yazd, Iran for their executive assistance.

Publisher Copyright:
© 2020, © 2020 Taylor & Francis Group, LLC.


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