The effect of smoking on early chorionic villous vascularisation

Robbert Oppenraaij; Anton Koning; MJB van den Hoff; Peter van der Spek; Eric Steegers; N. Exalto

doi:10.1016/j.placenta.2012.05.007

The effect of smoking on early chorionic villous vascularisation

Robbert Oppenraaij, Anton Koning, MJB van den Hoff, Peter van der Spek, Eric Steegers, Exalto

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

The aim aim of the study was to investigate whether first trimester chorionic villous vascularisation is different in women who smoked cigarettes before and during pregnancy in comparison with women who did not smoke. Placentas of smoking (>10 cigarettes/day, n = 13) and non-smoking women (n = 13), scheduled for a legal termination of a viable first trimester pregnancy for social indications, were retrieved. Placental tissues of 3-5 mm(3) were whole mount CD31 immunofluorescence stained. Images of the CD31 immunofluorescence and contour of the villi were captured using an Optical Projection Tomography scanner. An immersive BARCO virtual reality system was used to create an enlarged interactive 3-dimensional h In conclusion, chorionic villous vascularisation is already altered in first trimester of pregnancy in women who smoked cigarettes before and during pregnancy. (C) 2012 Elsevier Ltd. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	645-651
Number of pages	7
Journal	Placenta
Volume	33
Issue number	8
DOIs	https://doi.org/10.1016/j.placenta.2012.05.007
Publication status	Published - 2012

Access to Document

10.1016/j.placenta.2012.05.007

http://hdl.handle.net/1765/60885

Cite this

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title = "The effect of smoking on early chorionic villous vascularisation",

abstract = "The aim aim of the study was to investigate whether first trimester chorionic villous vascularisation is different in women who smoked cigarettes before and during pregnancy in comparison with women who did not smoke. Placentas of smoking (>10 cigarettes/day, n = 13) and non-smoking women (n = 13), scheduled for a legal termination of a viable first trimester pregnancy for social indications, were retrieved. Placental tissues of 3-5 mm(3) were whole mount CD31 immunofluorescence stained. Images of the CD31 immunofluorescence and contour of the villi were captured using an Optical Projection Tomography scanner. An immersive BARCO virtual reality system was used to create an enlarged interactive 3-dimensional h In conclusion, chorionic villous vascularisation is already altered in first trimester of pregnancy in women who smoked cigarettes before and during pregnancy. (C) 2012 Elsevier Ltd. All rights reserved.",

author = "Robbert Oppenraaij and Anton Koning and {van den Hoff}, MJB and {van der Spek}, Peter and Eric Steegers and Exalto",

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T1 - The effect of smoking on early chorionic villous vascularisation

AU - Oppenraaij, Robbert

AU - Koning, Anton

AU - van den Hoff, MJB

AU - van der Spek, Peter

AU - Steegers, Eric

AU - Exalto, null

PY - 2012

Y1 - 2012

N2 - The aim aim of the study was to investigate whether first trimester chorionic villous vascularisation is different in women who smoked cigarettes before and during pregnancy in comparison with women who did not smoke. Placentas of smoking (>10 cigarettes/day, n = 13) and non-smoking women (n = 13), scheduled for a legal termination of a viable first trimester pregnancy for social indications, were retrieved. Placental tissues of 3-5 mm(3) were whole mount CD31 immunofluorescence stained. Images of the CD31 immunofluorescence and contour of the villi were captured using an Optical Projection Tomography scanner. An immersive BARCO virtual reality system was used to create an enlarged interactive 3-dimensional h In conclusion, chorionic villous vascularisation is already altered in first trimester of pregnancy in women who smoked cigarettes before and during pregnancy. (C) 2012 Elsevier Ltd. All rights reserved.

AB - The aim aim of the study was to investigate whether first trimester chorionic villous vascularisation is different in women who smoked cigarettes before and during pregnancy in comparison with women who did not smoke. Placentas of smoking (>10 cigarettes/day, n = 13) and non-smoking women (n = 13), scheduled for a legal termination of a viable first trimester pregnancy for social indications, were retrieved. Placental tissues of 3-5 mm(3) were whole mount CD31 immunofluorescence stained. Images of the CD31 immunofluorescence and contour of the villi were captured using an Optical Projection Tomography scanner. An immersive BARCO virtual reality system was used to create an enlarged interactive 3-dimensional h In conclusion, chorionic villous vascularisation is already altered in first trimester of pregnancy in women who smoked cigarettes before and during pregnancy. (C) 2012 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.placenta.2012.05.007

DO - 10.1016/j.placenta.2012.05.007

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VL - 33

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