The effectiveness of supplemental and replacement blended cognitive behavioral therapy for internalizing disorders: a meta-analysis

  • Sara L.M. Velthuizen*
  • , Miranda C. Lutz
  • , Esther van den Bos
  • , Anne C. Miers
  • , P. Michiel Westenberg
  • *Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Blended cognitive behavioral therapy (bCBT) combines the use of traditional in-clinic, face-to-face therapy sessions with online therapy platforms. The blended aspect can either be supplementary to face-to-face sessions, or a partial replacement of face-to-face sessions. While bCBT has been available for two decades, there is no statistically synthesized overview of its effectiveness in treating internalizing disorders, including anxiety and depression. In this study, we examined effectiveness in two meta-analyses: 1) comparing bCBT to treatment as usual; 2) comparing bCBT change scores from pre- to post-treatment. We tested the influence of moderators on effectiveness: blended method, online therapist contact, and diagnosis. In line with expectations, results from meta-analysis one (k = 19 studies, N = 2749) showed that supplementary bCBT leads to a significantly superior treatment effect over treatment as usual (Cohen’s d = 0.41, 95% CI [0.24, 0.59]) while replacement bCBT is on par with treatment as usual (d = -0.01, 95% CI [−0.18, 0.17]). Meta-analysis two included 32 studies (N = 1895) and showed significant improvement with bCBT (Morris’s D = 1.12, 95% CI [0.92, 1.33]), irrespective of blended method or therapist contact. Findings suggest that bCBT is a worthwhile form of treatment for both anxiety and depression.

Original languageEnglish
Number of pages19
JournalCognitive Behaviour Therapy
DOIs
Publication statusE-pub ahead of print - 6 Nov 2025

Bibliographical note

Publisher Copyright:
© 2025 Swedish Association for Behaviour Therapy.

Research programs

  • ESSB PSY

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