Abstract
Original language | Undefined/Unknown |
---|---|
Pages (from-to) | 115-208 |
Number of pages | 94 |
Journal | Haematologica |
Volume | 101 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2016 |
Research programs
- EMC MGC-02-13-02
- EMC MM-02-41-03
- EMC MM-02-41-04
- EMC MM-02-54-03
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In: Haematologica, Vol. 101, No. 2, 2016, p. 115-208.
Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - The European Hematology Association Roadmap for European Hematology Research: a consensus document
AU - Engert, A
AU - Balduini, C
AU - Brand, A
AU - Coiffier, B
AU - Cordonnier, C
AU - Dohner, H
AU - de Wit, TD
AU - Eichinger, S
AU - Fibbe, W
AU - Green, T
AU - de Haas, F
AU - Iolascon, A
AU - Jaffredo, T
AU - Rodeghiero, F
AU - Salles, G
AU - Schuringa, JJ
AU - Andre, M
AU - Andre-Schmutz, I
AU - Bacigalupo, A
AU - Bochud, PY
AU - den Boer, Monique
AU - Bonini, C
AU - Camaschella, C
AU - Cant, A
AU - Cappellini, MD
AU - Cazzola, M
AU - Lo Celso, C
AU - Dimopoulos, M
AU - Douay, L
AU - Dzierzak, Elaine
AU - Einsele, H
AU - Ferreri, A
AU - De Franceschi, L
AU - Gaulard, P
AU - Gottgens, B
AU - Greinacher, A
AU - Gresele, P
AU - Gribben, J
AU - de Haan, G
AU - Hansen, JB
AU - Hochhaus, A
AU - Kadir, R
AU - Kaveri, S
AU - Kouskoff, V
AU - Kuhne, T
AU - Kyrle, P
AU - Ljungman, P
AU - Maschmeyer, G
AU - Mendez-Ferrer, S
AU - Milsom, M
AU - Mummery, C
AU - Ossenkoppele, G
AU - Pecci, A
AU - Peyvandi, F
AU - Philipsen, Sjaak
AU - Reitsma, P
AU - Ribera, JM
AU - Risitano, A
AU - Rivella, S
AU - Ruf, W
AU - Schroeder, T
AU - Scully, M
AU - Socie, G
AU - Staal, F
AU - Stanworth, S
AU - Stauder, R
AU - Stilgenbauer, S
AU - Tamary, H
AU - Theilgaard-Monch, K
AU - Thein, SL
AU - Tilly, H
AU - Trneny, M
AU - Vainchenker, W
AU - Vannucchi, AM
AU - Viscoli, C
AU - Vrielink, H
AU - Zaaijer, H
AU - Zanella, A
AU - Zolla, L
AU - Zwaginga, JJ
AU - Martinez, PA
AU - van den Akker, E
AU - Allard, S
AU - Anagnou, N
AU - Andrau, JC
AU - Angelucci, E
AU - Anstee, D
AU - Aurer, I
AU - Avet-Loiseau, H
AU - Aydinok, Y
AU - Bakchoul, T
AU - Balduini, A
AU - Barcellini, W
AU - Baruch, D
AU - Baruchel, A
AU - Bayry, J
AU - Bento, C
AU - van den Berg, A (Andrea)
AU - Bernardi, R
AU - Bianchi, P
AU - Bigas, A
AU - Biondi, A
AU - Bohonek, M
AU - Bonnet, D
AU - Borchmann, P
AU - Borregaard, N
AU - Braekkan, S
AU - ten Brink, M (Mirian)
AU - Brodin, E
AU - Bullinger, L
AU - Buske, C
AU - Butzeck, B
AU - Cammenga, J
AU - Campo, E
AU - Carbone, A
AU - Cervantes, F
AU - Cesaro, S
AU - Charbord, P
AU - Claas, F
AU - Cohen, H
AU - Conard, J
AU - Coppo, P
AU - Corrons, JLV
AU - da Costa, L
AU - Davi, F
AU - Delwel, Ruud
AU - Dianzani, I
AU - Domanovic, D
AU - Donnelly, P
AU - Drnovsek, TD
AU - Dreyling, M
AU - Du, MQ
AU - Durand, CML (Charles)
AU - Efremov, D
AU - Eleftheriou, A
AU - Elion, J
AU - Emonts, Marieke
AU - Engelhardt, M
AU - Ezine, S
AU - Falkenburg, F
AU - Favier, R
AU - Federico, M
AU - Fenaux, P
AU - Fitzgibbon, J
AU - Flygare, J
AU - Foa, R
AU - Forrester, L
AU - Galacteros, F
AU - Garagiola, I
AU - Gardiner, C
AU - Garraud, O
AU - van Geet, C
AU - Geiger, H
AU - Geissler, J
AU - Germing, U
AU - Ghevaert, C
AU - Girelli, D
AU - Godeau, B
AU - Gokbuget, N
AU - Goldschmidt, H
AU - Goodeve, A
AU - Graf, T
AU - Graziadei, G
AU - Griesshammer, M
AU - Gruel, Y
AU - Guilhot, F
AU - von Gunten, S
AU - Gyssens, I
AU - Halter, J
AU - Harrison, C
AU - Harteveld, C
AU - Hellstrom-Lindberg, E
AU - Hermine, O
AU - Higgs, D
AU - Hillmen, P
AU - Hirsch, H
AU - Hoskin, P
AU - Huls, G
AU - Inati, A
AU - Johnson, P
AU - Kattamis, A
AU - Kiefel, V
AU - Kleanthous, M
AU - Klump, H
AU - Krause, D
AU - Hovinga, JK
AU - Lacaud, G
AU - Lacroix-Desmazes, S
AU - Landman-Parker, J
AU - LeGouill, S
AU - Lenz, G
AU - von Lilienfeld-Toal, M
AU - Lindern, Marieke
AU - Lopez-Guillermo, A
AU - Lopriore, E
AU - Lozano, M
AU - Macintyre, E
AU - Makris, M
AU - Martens, John
AU - Mathas, S
AU - Matzdorff, A
AU - Medvinsky, A
AU - Menendez, P
AU - Migliaccio, AR
AU - Miharada, K
AU - Mikulska, M
AU - Minard, V
AU - Montalban, C
AU - de Montalembert, M
AU - Montserrat, E
AU - Morange, PE
AU - Mountford, J
AU - Muckenthaler, M
AU - Muller-Tidow, C
AU - Mumford, A
AU - Nadel, B
AU - Navarro, JT
AU - el Nemer, W
AU - Noizat-Pirenne, F
AU - O'Mahony, B
AU - Oldenburg, J
AU - Olsson, M
AU - Oostendorp, R
AU - Palumbo, A
AU - Passamonti, F
AU - Patient, R
AU - de Latour, RP
AU - Pflumio, F
AU - Pierelli, L
AU - Piga, A
AU - Pollard, D
AU - Raaijmakers, M
AU - Radford, J
AU - Rambach, R
AU - Rao, AK
AU - Raslova, H
AU - Rebulla, P
AU - Rees, D
AU - Ribrag, V
AU - Rijneveld, Anita
AU - Rinalducci, S
AU - Robak, T
AU - Roberts, I
AU - Rodrigues, C
AU - Rosendaal, F
AU - Rosenwald, A
AU - Rule, S
AU - Russo, R
AU - Saglio, G
AU - Sanchez, M
AU - Scharf, RE
AU - Schlenke, P
AU - Semple, J
AU - Sierra, J
AU - So-Osman, C
AU - Soria, JM
AU - Stamatopoulos, K
AU - Stegmayr, B
AU - Stunnenberg, H
AU - Swinkels, D
AU - Barata, JPT
AU - Taghon, T
AU - Taher, A
AU - Terpos, E
AU - Thachil, J
AU - Tissot, JD
AU - Touw, Ivo
AU - Toye, A
AU - Trappe, R
AU - Traverse-Glehen, A
AU - Unal, S
AU - Vaulont, S
AU - Viprakasit, V
AU - Vitolo, U
AU - van Wijk, R
AU - Wojtowicz, A
AU - Zeerleder, S
AU - Zieger, B
PY - 2016
Y1 - 2016
N2 - The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at (sic)23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
AB - The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at (sic)23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
U2 - 10.3324/haematol.2015.136739
DO - 10.3324/haematol.2015.136739
M3 - Article
C2 - 26819058
SN - 0390-6078
VL - 101
SP - 115
EP - 208
JO - Haematologica
JF - Haematologica
IS - 2
ER -