TY - JOUR
T1 - The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin
AU - Nijenhuis-Noort, Eline C.
AU - Berk, Kirsten A.
AU - Neggers, Sebastian J.C.M.M.
AU - van der Lely, Aart J.
N1 - Publisher Copyright:
Copyright © 2024 Korean Endocrine Society.
PY - 2024/1/9
Y1 - 2024/1/9
N2 - This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right decisions on how to intervene and improve metabolism for the benefit of patients, and to understand why and how metabolism responds in their specific cases. We will specifically address the interplay between GH, IGF-1, and insulin in type 1 and 2 diabetes mellitus, liver cirrhosis, and acromegaly as examples in which this knowledge is truly necessary.
AB - This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right decisions on how to intervene and improve metabolism for the benefit of patients, and to understand why and how metabolism responds in their specific cases. We will specifically address the interplay between GH, IGF-1, and insulin in type 1 and 2 diabetes mellitus, liver cirrhosis, and acromegaly as examples in which this knowledge is truly necessary.
UR - http://www.scopus.com/inward/record.url?scp=85186979753&partnerID=8YFLogxK
U2 - 10.3803/EnM.2024.101
DO - 10.3803/EnM.2024.101
M3 - Review article
C2 - 38192102
AN - SCOPUS:85186979753
SN - 2093-596X
VL - 39
SP - 83
EP - 89
JO - Endocrinology and Metabolism
JF - Endocrinology and Metabolism
IS - 1
ER -
