The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

Eline C. Nijenhuis-Noort; Kirsten A. Berk; Sebastian J.C.M.M. Neggers; Aart J. van der Lely

doi:10.3803/EnM.2024.101

The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

Eline C. Nijenhuis-Noort
, Kirsten A. Berk
, Sebastian J.C.M.M. Neggers
, Aart J. van der Lely^*

^*Corresponding author for this work

Internal Medicine

Erasmus University Rotterdam

Research output: Contribution to journal › Review article › Academic › peer-review

56 Citations (Scopus)

132 Downloads (Pure)

Abstract

This review intends to provide the reader with a practical overview of several (patho)physiological conditions in which knowledge of the interplay between growth hormone (GH), insulin-like growth factor-1 (IGF-1), and insulin is important. This might help treating physicians in making the right decisions on how to intervene and improve metabolism for the benefit of patients, and to understand why and how metabolism responds in their specific cases. We will specifically address the interplay between GH, IGF-1, and insulin in type 1 and 2 diabetes mellitus, liver cirrhosis, and acromegaly as examples in which this knowledge is truly necessary.

Original language	English
Pages (from-to)	83-89
Number of pages	7
Journal	Endocrinology and Metabolism
Volume	39
Issue number	1
DOIs	https://doi.org/10.3803/EnM.2024.101
Publication status	Published - 9 Jan 2024

Bibliographical note

Publisher Copyright:
Copyright © 2024 Korean Endocrine Society.

UN SDGs

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SDG 3 Good Health and Well-being

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The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and InsulinFinal published version, 599 KBLicence: CC BY

Cite this

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The Fascinating Interplay between Growth Hormone, Insulin-Like Growth Factor-1, and Insulin

Abstract

Bibliographical note

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