Abstract
The value of mapping musical function during awake craniotomy is unclear. Hence, this systematic review was conducted to examine the feasibility and added value of music mapping in patients undergoing awake craniotomy. An extensive search, on 26 March 2021, in four electronic databases (Medline, Embase, Web of Science and Cochrane CENTRAL register of trials), using synonyms of the words "Awake Craniotomy" and "Music Performance," was conducted. Patients performing music while undergoing awake craniotomy were independently included by two reviewers. This search resulted in 10 studies and 14 patients. Intra-operative mapping of musical function was successful in 13 out of 14 patients. Isolated music disruption, defined as disruption during music tasks with intact language/speech and/or motor functions, was identified in two patients in the right superior temporal gyrus, one patient in the right and one patient in the left middle frontal gyrus and one patient in the left medial temporal gyrus. Pre-operative functional MRI confirmed these localizations in three patients. Assessment of post-operative musical function, only conducted in seven patients by means of standardized (57%) and non-standardized (43%) tools, report no loss of musical function. With these results, we conclude that mapping music is feasible during awake craniotomy. Moreover, we identified certain brain regions relevant for music production and detected no decline during follow-up, suggesting an added value of mapping musicality during awake craniotomy. A systematic approach to map musicality should be implemented, to improve current knowledge on the added value of mapping musicality during awake craniotomy.
| Original language | English |
|---|---|
| Pages (from-to) | 388-404 |
| Number of pages | 17 |
| Journal | European Journal of Neuroscience |
| Volume | 55 |
| Issue number | 2 |
| Early online date | 10 Dec 2021 |
| DOIs | |
| Publication status | Published - Jan 2022 |
Bibliographical note
Funding Information:This study was funded by the Erasmus University Medical Center. The funders of the study had no role in the study design, data collection, data analysis, manuscript preparation and publication decision. PK coordinated this study. PK and TB conducted the literature search, extracted the data, conducted the statistical analysis and wrote the first draft of the manuscript. PK, AV, DS, CD, JJ and MK interpreted the data and critically revised the manuscript. PK, TB, AV, DS, CD, JJ and MK had full access to all of the data in the study and can take responsibility for the integrity of the data and the accuracy of the data analysis.
Publisher Copyright:
© 2021 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.