The feasibility and safety of applying the Magnetic Navigation System to manage chronically occluded vessels: a single centre experience

S Ramcharitar, Wim Giessen, M van der Ent, Pim Feijter, PWJC (Patrick) Serruys, Robert Jan van Geuns

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7 Citations (Scopus)


Aims: Applying the Magnetic Navigation System (MNS) to manage chronic total occlusions (CTOs). The MNS precisely directs a magnetised guidewire in vivo through two permanent external magnets. Methods and results: The first 43 consecutive MNS treated CTOs were retrospectively evaluated. Computed tomography coronary angiography (CTCA) co-integration with the MNS provided a virtual road map through the occlusion. Unsuccessful MNS cases were managed with bailout conventional guidewire techniques. Experienced CTO and MNS operators had unrestricted access to CTO devices and equipments. The MNS crossing success increased from 40% to 56% over 52 months and averaged 44.2% (19/43 patients). In 58.3% (14/24) of failed MNS cases the conventional wire approach was successful, giving an overall procedural success rate of 76.6%. Of those conventionally treated, two patients required pericardiocentesis. On average, 1.8 +/- 0.9 stents (lengths 44.7 +/- 21.4 mm and diameter 2.8 +/- 0.4 mm) were implanted. Procedural times were lengthy (125.0 +/- 35.3 min) requiring high fluoroscopy dosage (11980.2 +/- 6457.9 Gy/cm(2)) and contrast media usage (388.8 +/- 170.2 ml). Operators persevered less with magnetic wires (20.9 +/- 12.4 min vs. 27.7 +/- 24.4 min), and preferentially used the least stiff wire as first choice (53.5%). CTCA co-integration did not influence procedural outcome. As with conventional wires, higher magnetic wire successes occurred in low calcified lesions, those with a central stump and without bridging collaterals. Conclusions: In unselected CTOs, the magnetic wires are safe and feasible. Current modest success rates with a high procedural bailout rate implicate the need for improved magnetic guidewire technology comparable to available sophisticated conventional CTO wires. Randomised studies are needed to clarify the value of magnetic guided recanalisation.
Original languageUndefined/Unknown
Pages (from-to)711-716
Number of pages6
Issue number6
Publication statusPublished - 2011

Research programs

  • EMC COEUR-09

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