The gold industry standard for risk and cost of drug and vaccine development revisited

Esther Pronker, Tamar Weenen, Harry Commandeur, Ab Osterhaus, Eric Claassen

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)

Abstract

Gold dimensions of pharmaceutical drug development indicate that it takes on average 11.9 years, with an investment around US$ 0.8 Billion, to launch one product on the market. Furthermore, approximately 22% of the drug candidates successfully complete clinical testing. These universally acknowledged proportions largely originate from one single, much cited publication: Dimasi et al. [5]. However an additional six articles describing new chemical entities (NCE) development were identified, which contain little, if any, information on vaccines. Published cumulative success rates range from 7% to 78% and investments calculations span US$ 0.8 to 1.7 Billion. Obviously this disserves further clarification? (C) 2011 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)5846-5849
Number of pages4
JournalVaccine
Volume29
Issue number35
DOIs
Publication statusPublished - 2011

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